Veterinary anaesthesia and analgesia
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Randomized Controlled Trial
Observations on the muscle relaxant rocuronium bromide in the horse--a dose-response study.
To investigate the onset and duration of neuromuscular blockade of rocuronium bromide and its associated haemodynamic effects at three doses in healthy horses. ⋯ Rocuronium is an effective nondepolarizing muscle relaxant in horses under isoflurane anaesthesia. It had a dose-dependent onset and duration of action. Rocuronium did not produce significant changes in the measured cardiovascular parameters.
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Randomized Controlled Trial
A study of the effect of hemorrhage on the cardiorespiratory actions of halothane, isoflurane and sevoflurane in the dog.
To compare the cardiorespiratory changes induced by equipotent concentrations of halothane (HAL), isoflurane (ISO) and sevoflurane (SEVO) before and after hemorrhage. ⋯ Inhaled anesthetics should be used judiciously in animals presented with blood loss. However, if an inhalational agent is to be used under these circumstances, ISO may provide better hemodynamic stability than SEVO or HAL.
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Randomized Controlled Trial
Comparison of isoflurane and sevoflurane for short-term anesthesia in piglets.
To compare isoflurane (ISO) and sevoflurane (SEVO) short-term anesthesia in piglets during castration. ⋯ Isoflurane and SEVO, delivered in a novel inhaler, provided economical, safe, rapid anesthetic induction and maintenance. Optimal conditions were provided for castration and recoveries were brief and smooth. Statistically significant differences in times would be of minor clinical importance. The cost of anesthesia was much less with ISO than with SEVO.
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Randomized Controlled Trial
Investigation of the interaction between buprenorphine and sufentanil during anaesthesia for ovariectomy in dogs.
To investigate the effect of buprenorphine pre-treatment on sufentanil requirements in female dogs undergoing ovariectomy. ⋯ Withholding buprenorphine therapy 6-8 hours before anaesthesia incorporating pure mu receptor agonists is probably advisable. Alternative methods of analgesia should be provided in this period.
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Randomized Controlled Trial
Differences in need for hemodynamic support in horses anesthetized with sevoflurane as compared to isoflurane.
To study whether hemodynamic function in horses, particularly mean arterial blood pressure (MAP), is better maintained with sevoflurane than isoflurane, thus requiring less pharmacological support. ⋯ Horses under sevoflurane anesthesia may require less pharmacological support in the form of dobutamine than isoflurane-anesthetized horses. This could be due to less suppression of vasomotor tone.