Veterinary anaesthesia and analgesia
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To measure concentrations of lidocaine serum after application of two 5% patches on horses. ⋯ Any analgesic effects that might be produced by application of 5% lidocaine patches on horses will not be due to systemic absorption of the drug.
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Randomized Controlled Trial
The isoflurane-sparing and clinical effects of a constant rate infusion of remifentanil in dogs.
To evaluate the isoflurane-sparing and clinical effects of two constant rate infusions of remifentanil in healthy dogs undergoing orthopaedic surgery. ⋯ Remifentanil infusions may be a useful additive to isoflurane anaesthesia in healthy dogs.
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To assess the changes in colloid osmotic pressure (COP) in horses undergoing surgery for colic. ⋯ Colloid osmotic pressure, like TP, decreased greatly over the course of crystalloid fluid infusion during anesthesia for laparotomy in horses with colic. This change may predispose the animal to tissue edema with subsequent morbidity.
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To estimate the risk of death and identify the major risk factors for peri-anaesthetic mortality in great apes (Hominidae) that underwent anaesthesia in zoological collections in the UK and Ireland between 1 January 1990 and 30 June 2005. ⋯ This study has shown that great ape anaesthesia appears to carry a high risk of mortality. Sick and aged patients are at an increased risk of death and particular care should be exercised during their anaesthesia. Standardisation and completeness of anaesthetic records across zoological collections would assist greatly in further studies.
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Randomized Controlled Trial
Use of ephedrine and dopamine in dogs for the management of hypotension in routine clinical cases under isoflurane anesthesia.
To determine the cardiovascular responses of ephedrine and dopamine for the management of presurgical hypotension in anesthetized dogs. ⋯ In anesthetized hypotensive dogs, ephedrine and dopamine improved cardiac output and oxygen delivery. However, the pressure-elevating effect of ephedrine is transient, while an infusion of dopamine at 10 microg kg(-1) minute(-1) improved MAP significantly by additionally maintaining TPR.