Veterinary anaesthesia and analgesia
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Case Reports
Accidental prehension and suspected transmucosal or oral absorption of fentanyl from a transdermal patch in a dog.
A 100-microg hour(-1) transdermal fentanyl patch was applied to a 29-kg, 6-year-old, intact male mixed breed dog to help manage postoperative pain after total ear canal ablation and lateral bulla osteotomy. Two days later, the dog was found extremely sedated, and the reservoir of the transdermal patch was open. ⋯ The patch was removed, blood was drawn to determine serum fentanyl levels, and the dog recovered without incident. This clinical case documents the potential for neurologic sequelae, and bradycardia when fentanyl patches are used in animals to relieve postoperative pain.
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To study Hemoglobin glutamer-200 bovine (Hb-200), 6% hetastarch (HES) and shed whole blood (WB) resuscitation in canine hemorrhagic shock. ⋯ Resuscitation with Hb-200 seemed to resolve metabolic acidosis and lactatemia more rapidly than HES, but not WB; yet it is not superior to HES in improving DO2I and DO2Im. The hyperoncotic property of solutions like Hb-200 that results in rapid volume expansion with more homogenous microvascular perfusion and the ability to facilitate diffusive O2 transfer accelerating metabolic recovery may be the key mechanisms underlying their beneficial effects as resuscitants.
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Randomized Controlled Trial
Investigation of the interaction between buprenorphine and sufentanil during anaesthesia for ovariectomy in dogs.
To investigate the effect of buprenorphine pre-treatment on sufentanil requirements in female dogs undergoing ovariectomy. ⋯ Withholding buprenorphine therapy 6-8 hours before anaesthesia incorporating pure mu receptor agonists is probably advisable. Alternative methods of analgesia should be provided in this period.
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To determine the prevalence of postanesthetic hyperthermia [rectal temperature >40 degrees C (104 degrees F)] in a clinical population of cats. ⋯ When hydromorphone is used in cats their body temperature should be closely monitored.
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Randomized Controlled Trial
Differences in need for hemodynamic support in horses anesthetized with sevoflurane as compared to isoflurane.
To study whether hemodynamic function in horses, particularly mean arterial blood pressure (MAP), is better maintained with sevoflurane than isoflurane, thus requiring less pharmacological support. ⋯ Horses under sevoflurane anesthesia may require less pharmacological support in the form of dobutamine than isoflurane-anesthetized horses. This could be due to less suppression of vasomotor tone.