The lancet oncology
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The lancet oncology · Feb 2018
ReviewPopulation-based cancer screening programmes in low-income and middle-income countries: regional consultation of the International Cancer Screening Network in India.
The reductions in cancer morbidity and mortality afforded by population-based cancer screening programmes have led many low-income and middle-income countries to consider the implementation of national screening programmes in the public sector. Screening at the population level, when planned and organised, can greatly benefit the population, whilst disorganised screening can increase costs and reduce benefits. ⋯ In this Series paper, we report outcomes of the first regional consultation of the ICSN held in Agartala, India (Sept 5-7, 2016), which included discussions from cancer screening programmes from Denmark, the Netherlands, USA, and Bangladesh. We outline six essential elements of population-based cancer screening programmes, and share recommendations from the meeting that policy makers might want to consider before implementation.
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The lancet oncology · Feb 2018
Randomized Controlled Trial Comparative StudyImproved progression-free survival in metastatic breast cancer.
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The lancet oncology · Feb 2018
Randomized Controlled TrialPEGPH20 for metastatic pancreatic ductal adenocarcinoma.
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The lancet oncology · Feb 2018
Inotuzumab ozogamicin in combination with low-intensity chemotherapy for older patients with Philadelphia chromosome-negative acute lymphoblastic leukaemia: a single-arm, phase 2 study.
Inotuzumab ozogamicin, an anti-CD22 monoclonal antibody bound to a toxin, calicheamicin, has shown single-agent activity in relapsed or refractory acute lymphoblastic leukaemia. We aimed to assess the activity and safety of inotuzumab ozogamicin in combination with low-intensity chemotherapy in older patients with acute lymphoblastic leukaemia. ⋯ MD Anderson Cancer Center.