The lancet oncology
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The lancet oncology · Jun 2004
Review Comparative StudySystematic review of taxane-containing versus non-taxane-containing regimens for adjuvant and neoadjuvant treatment of early breast cancer.
The use of taxanes in early breast cancer is increasing. However, there are few mature studies of taxanes in this setting, and their role is uncertain. Our systematic review of randomised trials of adjuvant or neoadjuvant systemic therapy identified ten reported trials comparing a taxane-containing group with a non-taxane-containing control group in women with early breast cancer. ⋯ Two trials showed a significant improvement in overall survival. These results support the use of adjuvant taxanes in women with early breast cancer and involved lymph nodes. Longer follow-up of these trials and results from continuing trials are needed to clarify the best use of taxanes in early breast cancer.
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The lancet oncology · Jun 2004
Comment Comparative StudyIntraoperative radiotherapy: the debate continues.
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Events in the past 10-15 years have meant that Iraq's once highly sophisticated health-care system has fallen to rack and ruin. To fight the very low morale, Iraqi people are making use of many approaches, some of which are unconventional, such as circus entertainment to raise spirits in paediatric wards. This Reportage looks at the events that have lead to the current health-care crisis in Iraq through the eyes of those living and working there. It is based on interviews done by Jo Wilding, an independent humanitarian activist and writer working on various grassroots rehabilitation and solidarity projects in Iraq, in Al Mansour teaching hospital, Shahid Adnan hospital, the centre for Nuclear Medicine, and the Ministry of Health in Baghdad.