Current pain and headache reports
The most recent articles from:
Curr Pain Headache Rep
-
Curr Pain Headache Rep · Jun 2007
Review Meta AnalysisControlled trials in pediatric migraine: crossover versus parallel group.
Studies on the treatment of migraine in children and adolescents are rare and difficult to design. In particular, the high placebo response makes it difficult to show efficacy of a verum drug. When analyzing all published trials in the acute drug treatment of migraine in children, crossover trials show lower placebo rates and higher therapeutic gain, compared with parallel group trials. This should be considered in the future design of acute drug trials in childhood migraine.