Swiss medical weekly
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Swiss medical weekly · Jan 2017
Medical use of cannabis in Switzerland: analysis of approved exceptional licences.
In recent years, the Swiss Federal Office of Public Health (FOPH) granted exceptional licenses for the medical use of cannabinoids, typically for 6 months with possible extensions. A systematic review of cannabinoids for medical use commissioned by the FOPH supports the use of cannabinoids for the treatment of chronic pain and spasticity. However, little is known about the patients treated with cannabinoids. We aimed to study medical uses of cannabinoids as part of the FOPH's programme of exceptional licenses. ⋯ Exceptional licences for medical use of cannabinoids have increased substantially in Switzerland, with the programme including patients with a wide range of conditions.
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Swiss medical weekly · Jan 2017
Role of liver magnetic resonance imaging in hyperferritinaemia and the diagnosis of iron overload.
Hyperferritinaemia is a frequent clinical problem. Elevated serum ferritin levels can be detected in different genetic and acquired diseases and can occur with or without anaemia. It is therefore important to determine whether hyperferritinaemia is due to iron overload or due to a secondary cause. ⋯ Signal intensity ratio may be a good adjunct to R2 and R2* methods as it allows easy visual estimation of the liver iron concentration. In this review a group of Swiss haematologists and radiologists give an overview of different conditions leading to primary or secondary iron overload and on diagnostic methods to assess hyperferritinaemia with a focus on the role of liver MRI. They summarise the standard practice in Switzerland on the use of liver iron concentration MRI as well as disease-specific guideline recommendations.
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Swiss medical weekly · Jan 2017
Temporal trends of postpartum haemorrhage in Switzerland: a 22-year retrospective population-based cohort study.
Postpartum haemorrhage (PPH) is one of the leading causes of maternal morbidity and mortality. Studies have reported an increase in incidence of postpartum haemorrhage in recent years. Our goal was to investigate changes in the incidence of postpartum haemorrhage (PPH) and its risk factors in Switzerland from 1993 to 2014. ⋯ Postpartum haemorrhage is a relatively common and potentially dangerous obstetric complication with increasing incidence over the last two decades in Switzerland. Its increase over time has been paralleled by an increase in uterine atony.
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Swiss medical weekly · Jan 2017
Oncological patients in the intensive care unit: prognosis, decision-making, therapies and end-of-life care.
The effectiveness of intensive care unit (ICU) care for cancer patients remains controversial. Advances in antitumour and supportive care led to major improvements in outcomes of oncological patients in the ICU. Improved cancer therapies and supportive management of organ dysfunctions have contributed to improved survival rates. ⋯ Establishment of clear goals and approach to admit and treatment for oncological patients in the ICU are however urgently needed. This requires further prospective studies for independent validation in different medical settings and identifying prognostic tools that can aid with decision-making and patient selection for ICU. Cancer should not be seen as an exclusion criterion and priority should be given to assure the quality of life of oncological patients.
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Swiss medical weekly · Jan 2017
Value of the Pitt Bacteraemia Score to predict short-term mortality in Staphylococcus aureus bloodstream infection: a validation study.
The widely used Pitt Bacteraemia Score (PBS) has repeatedly been described as a risk factor for short-term mortality in Staphylococcus aureus bloodstream infection (BSI), but little is known about its overall predictive performance. We therefore aimed to externally validate the PBS in S. aureus BSIs. ⋯ For short-term mortality, the PBS had a low predictive value in a patient population with methicillin-susceptible S. aureus BSI. There is a need to improve simple clinical scores to better predict mortality, in particular for S. aureus.