Clinical medicine (London, England)
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An increasingly common scenario on the acute medical take is that of 'possible pulmonary embolism'. The aim of this article is to update the reader about the available clinical decision tools that can help to avoid the over investigation of such patients, as well as other tools that can support an outpatient management strategy in appropriate patient groups. ⋯ We address the evidence on the long-term risk of venous thromboembolism recurrence and show how this can be used to make decisions about duration of anticoagulation. Finally, we discuss a number of special scenarios, including the implications of incidentally discovered isolated subsegmental pulmonary embolus and the management of pulmonary embolus in malignancy and pregnancy.
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Case Reports
Lessons of the month 2: Retinal vasculitis: a first presentation of Takayasu's arteritis.
Takayasu's arteritis is a chronic, systemic, large-vessel vasculitis affecting the aorta and its primary branches. However, coronary, renal and pulmonary arteries and small vessel involvement has been documented. We describe a rare case of Takayasu's arteritis with extensive supra-aortic arch disease, manifesting with bilateral occlusive retinal vasculitis as a first presentation. This is elicited by fundus findings of vascular sheathing and fundus fluoresceine angiography evidence of retinal vessel occlusion and peripheral capillary non-perfusion.
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The Royal College of Physicians' COVID-19 study was conducted in 2020 as a collaboration of 19 English NHS trusts, the Association of Professional Healthcare Analysts and a data team in the Institute of Global Health Innovation at Imperial College London. The participating trusts had a combined catchment population of 10.46 million and looked after over 26,000 patients with SARS-CoV-2. The study involved 510 patient cases the majority of which were mortality reviews. ⋯ Poor care was uncommon. Qualitative data generated 24 common themes that were articulated by the creation of nine vignettes (four explored here). Six recommendations were created, and further analysis of specific recommendations is advised.