Article
Cumulative duration of "triple low" state of low blood pressure, low bispectral index, and low minimum alveolar concentration of volatile anesthesia is not associated with increased mortality.
Anesthesiology. 2014 Jul 1; 121 (1): 18-28.
Article
Prolonged concurrent hypotension and low bispectral index ('double low') are associated with mortality, serious complications, and prolonged hospitalization after cardiac surgery.
Br J Anaesth. 2017 Jul 1; 119 (1): 40-49.
Randomized Controlled Trial
Association of perioperative risk factors and cumulative duration of low bispectral index with intermediate-term mortality after cardiac surgery in the B-Unaware Trial.
Anesthesiology. 2010 May 1;112(5):1116-27.