Articles: kwashiorkor.
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Pediatr. Infect. Dis. J. · Nov 1994
The etiology of pneumonia in malnourished and well-nourished Gambian children.
During a 2-year period 159 malnourished children ages 3 months to 5 years with radiologic evidence of pneumonia were investigated to determine the cause of their pneumonia. In addition 119 malnourished children without pneumonia, 119 well-nourished children with pneumonia and 52 well-nourished children without pneumonia were studied as controls. Percutaneous lung aspiration was performed on 35 malnourished and 59 well-nourished children with pneumonia. ⋯ Mycobacterium tuberculosis was detected in 5 malnourished children with pneumonia. A potentially pathogenic virus was identified in 35% of malnourished children with pneumonia and 40% of well-nourished children with pneumonia, and from 25% of children without pneumonia. The viruses identified most frequently were adenovirus and respiratory syncytial virus.(ABSTRACT TRUNCATED AT 250 WORDS)
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Cross-sectional morbidity recorded during two successive quarterly survey rounds and subsequent 27-months mortality were studied in a random sample of 4238 preschool children in a rural Zairian area. Analysis focuses on morbid patterns, i.e. any combination of the principal signs and symptoms encountered in tropical areas (oedema, marasmus, cough, fever, diarrhoea and tachypnoea). Almost half the children (45-48%) had signs of morbidity, a very high rate. ⋯ The results show that with a few simple questions on major symptoms and a brief examination by paramedical health workers, children with an increased risk of death can be identified. The method can be applied at under-5 clinics. Prognosis is particularly bad in severe malnutrition, especially when associated with diarrhoea, in diarrhoea with cough, cough with fever/tachypnoea and for children who are found sick both in the rainy and the subsequent dry season.
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In a study of 7,631 cases referred to the infectious diseases hospital, Nairobi with a diagnosis of measles, 7,447 cases had the diagnosis confirmed. The overall mortality was 17.5 per 1000 cases with 43.51 of all the deaths occurring in all children less than 12 months of age. A nutritional analysis revealed that children whose weight were below 80 of the Harvard median of weight for age stayed in hospital longest and had the highest mortality rate. Measles continues to offer increasing challenge in spite of the intensive vaccination programme presently being carried out.