Articles: analgesics.
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Anaesth Intensive Care · Oct 1995
Randomized Controlled Trial Clinical TrialRectal indomethacin potentiates spinal morphine analgesia after caesarean delivery.
This double-blind, randomized study was designed to evaluate the use of indomethacin (Indocid, MSD) following caesarean delivery performed under spinal anaesthesia. Thirty ASA I-II women presenting for elective caesarean were recruited. Spinal anaesthesia was performed in a standard manner using hyperbaric bupivacaine, fentanyl and morphine. ⋯ There were no reported adverse neonatal or maternal effects from the use of indomethacin. Rectal indomethacin use following caesarean delivery leads to significantly improved pain relief compared with placebo. The combination of spinal morphine and rectal indomethacin leads to high-quality postoperative analgesia.
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J. Cardiothorac. Vasc. Anesth. · Oct 1995
Randomized Controlled Trial Comparative Study Clinical TrialPain outcomes after thoracotomy: lumbar epidural hydromorphone versus intrapleural bupivacaine.
To evaluate postthoractomy analgesia in patients receiving lumbar epidural hydromorphone versus intrapleural bupivacaine. ⋯ Epidural hydromorphone is superior to intrapleural bupivacaine in achieving satisfactory pain outcomes during the first 5 hours after thoracotomy.
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J. Cardiothorac. Vasc. Anesth. · Oct 1995
Randomized Controlled Trial Clinical TrialEffects of thoracic epidural analgesia on coronary hemodynamics and myocardial metabolism in coronary artery bypass surgery.
A possible influence of thoracic epidural analgesia on coronary hemodynamics and myocardial metabolism in coronary artery bypass grafting was investigated. ⋯ With regard to the coronary circulation and myocardial metabolism, no hard data supporting the use of thoracic epidural analgesia in coronary artery bypass grafting were found.
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J. Cardiothorac. Vasc. Anesth. · Oct 1995
Randomized Controlled Trial Comparative Study Clinical TrialComparison of intrapleural versus intravenous morphine for postthoracotomy pain management.
To compare the analgesic effects of intrapleural and intravenous morphine administration for postthoracotomy pain management. ⋯ IPM achieved better analgesia than IVM and this effect is probably attributable to peripheral effects of morphine.
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Randomized Controlled Trial Comparative Study Clinical Trial Controlled Clinical Trial
Comparison of i.m. and local infiltration of ketorolac with and without local anaesthetic.
We have studied postoperative analgesia in 32 patients undergoing outpatient repair of inguinal hernia. All patients received a standardized general anaesthetic of thiopentone followed by halothane or isoflurane in 70% nitrous oxide and oxygen delivered by face mask or laryngeal mask with spontaneous ventilation. No patient received premedication, opioids or neuromuscular blockers. ⋯ There were no significant differences in pain scores at any time between the three study groups. Wound infiltration with ketorolac 30 mg in saline, 0.25% bupivacaine or ketorolac 30 mg with 0.25% bupivacaine provided equivalent analgesia. Wound infiltration with ketorolac 30 mg in saline provided analgesia superior to that of ketorolac 60 mg i.m.