Articles: palliative-care.
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Randomized Controlled Trial Multicenter Study
The effects of low doses of pregabalin on morphine analgesia in advanced cancer patients.
The aim of this study was to evaluate the opioid response in patients receiving morphine and pregabalin, independently from the presumed pain mechanisms, in comparison with patients receiving morphine treatment only. ⋯ The use of low doses of pregabalin added to morphine therapy in advanced cancer patients does not seem to provide advantageous analgesic effects, despite limitations of the present study due to the number of drop-outs.
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Randomized Controlled Trial
Neuromuscular electrical stimulation of the quadriceps in patients with non-small cell lung cancer receiving palliative chemotherapy: a randomized phase II study.
A reduced exercise capacity is associated with increased morbidity and mortality in patients with advanced non-small cell lung cancer (NSCLC). Therapeutic exercise can be beneficial and neuromuscular electrical stimulation (NMES) of the quadriceps muscles may represent a practical approach. The primary aim of this study was to determine the acceptability of NMES of the quadriceps to patients with NSCLC used alongside palliative chemotherapy. Secondary aims explored aspects of safety and efficacy of NMES in this setting. ⋯ NMES is not acceptable in this setting, nor was there a suggestion of benefit. The need remains to explore NMES in patients with cancer in other settings.
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Support Care Cancer · Jan 2013
Randomized Controlled TrialThe impact of individual quality of life assessment on psychosocial attention in patients with chest malignancies: a randomized study.
The aims of this study were to investigate the impact of individual health-related quality of life (HRQL) evaluation on the attention towards symptom control and psychosocial function in advanced cancer patients. ⋯ Individual HRQL assessment increased the attention to psychosocial functioning in patients with chest malignancies.
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Randomized Controlled Trial
Referral practices of oncologists to specialized palliative care.
To describe current referral practices of oncologists to specialized palliative care (SPC) and define demographic characteristics, practice situations, and opinions associated with referral. ⋯ Oncologists referred patients frequently to SPC, but generally late in the disease course for patients with uncontrolled symptoms. Availability of comprehensive SPC, especially for patients receiving chemotherapy, and persisting definitional issues seem to be the main barriers preventing timely referral.
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Journal of medical ethics · Dec 2012
Randomized Controlled TrialDefault options and neonatal resuscitation decisions.
To determine whether presenting delivery room management options as defaults influences decisions to resuscitate extremely premature infants. ⋯ Presenting delivery room options for extremely premature infants as defaults may compromise autonomous decision-making.