Articles: mechanical-ventilation.
-
Pediatric pulmonology · Jan 2015
Randomized Controlled TrialNeurally adjusted ventilatory assist (NAVA) in pediatric intensive care--a randomized controlled trial.
Neurally adjusted ventilatory assist (NAVA) has been shown to improve patient-ventilator synchrony during invasive ventilation. The aim of this trial was to study NAVA as a primary ventilation mode in pediatric intensive care and to compare it with current standard ventilation modes. ⋯ We found NAVA to be a safe and feasible primary ventilation mode for use with children. It outscored standard ventilation in some aspects, as it was able to enhance oxygenation even at lower airway pressures and led to reduced use of sedatives during longer periods of treatment.
-
Randomized Controlled Trial
Effect of heated humidified ventilation on bronchial mucus transport velocity in general anaesthesia: a randomized trial.
To evaluate the effects of heated humidified ventilation on mucociliary function during general anaesthesia. ⋯ Heated humidified ventilation effectively maintains mucociliary clearance of patients during sevoflurane general anaesthesia.
-
Editorial Randomized Controlled Trial Multicenter Study
THE ASSOCIATION BETWEEN PHYSIOLOGIC DEAD-SPACE FRACTION AND MORTALITY IN PATIENTS WITH THE ACUTE RESPIRATORY DISTRESS SYNDROME ENROLLED INTO A PROSPECTIVE MULTI-CENTERED CLINICAL TRIAL.
We tested the association between pulmonary dead-space fraction (ratio of dead space to tidal volume [V(D)/V(T)]) and mortality in subjects with ARDS (Berlin definition, P(aO2)/F(IO2) ≤ 300 mm Hg; PEEP ≥ 5 cm H2O) enrolled into a clinical trial incorporating lung-protective ventilation. ⋯ Markedly elevated V(D)/V(T) (≥ 0.60) in early ARDS is associated with higher mortality. Measuring V(D)/V(T) may be useful in identifying ARDS patients at increased risk of death who are enrolled into a therapeutic trial.
-
Randomized Controlled Trial Comparative Study
In COPD patients on prolonged mechanical ventilation heart rate variability during the T-piece trial is better after pressure support plus PEEP: a pilot physiological study.
To evaluate heart rate variability (HRV), hemodynamics, mechanics, dyspnea and blood gases following different mechanical ventilation (MV) settings. ⋯ The T-piece trial following setting-2 seems less stressful on neural control of HRV. Future studies on T-piece trials should consider the residual effect of the MV setting.
-
Randomized Controlled Trial
Impact of tracheostomy placement on anxiety in mechanically ventilated adult ICU patients.
To determine if self-reported anxiety levels decreased after tracheostomy placement in a sample of mechanically ventilated intensive care unit patients. ⋯ Prospective studies are needed to more accurately assess the impact of tracheostomy placement on patient anxiety and salient outcomes.