Articles: dosage.

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• Med Lett Drugs Ther · Nov 2019

  Review

  Upadacitinib (Rinvoq) - a new JAK inhibitor for rheumatoid arthritis.

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• Med Lett Drugs Ther · Sep 2019

  Review

  Lefamulin (Xenleta) for community-acquired bacterial pneumonia.

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• Med Lett Drugs Ther · Aug 2019

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  Drugs for anxiety disorders.

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• Med Lett Drugs Ther · Jul 2019

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  Zolgensma - one-time gene therapy for spinal muscular atrophy.

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• Crit Care · Mar 2019

  Review

  Optimization of the treatment with beta-lactam antibiotics in critically ill patients-guidelines from the French Society of Pharmacology and Therapeutics (Société Française de Pharmacologie et Thérapeutique-SFPT) and the French Society of Anaesthesia and Intensive Care Medicine (Société Française d'Anesthésie et Réanimation-SFAR).

  Beta-lactam antibiotics (βLA) are the most commonly used antibiotics in the intensive care unit (ICU). ICU patients present many pathophysiological features that cause pharmacokinetic (PK) and pharmacodynamic (PD) specificities, leading to the risk of underdosage. The French Society of Pharmacology and Therapeutics (SFPT) and the French Society of Anaesthesia and Intensive Care Medicine (SFAR) have joined forces to provide guidelines on the optimization of beta-lactam treatment in ICU patients. ⋯ The experts strongly suggest the use of personalized dosing, continuous or prolonged infusion and therapeutic drug monitoring when administering βLA in critically ill patients.

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