Articles: middle-aged.
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Smoking is known to be a major cause of death among middle-aged adults, but evidence on its impact and the benefits of smoking cessation among older adults has remained limited. Therefore, we aimed to estimate the influence of smoking and smoking cessation on all-cause mortality in people aged ≥60 years. ⋯ Smoking remains as a strong risk factor for premature mortality in older individuals and cessation remains beneficial even at advanced ages. Efforts to support smoking abstinence at all ages should be a public health priority.
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To determine the heritability of spine curve using plain radiographs and to identify risk factors for spine curvature including age, body mass index, smoking, bone mineral density (BMD), and lumbar disc degeneration (LDD). ⋯ In this sample of middle-aged and elderly women, there were significant genetic influences on all spine curves but particularly thoracic kyphosis and lumbar lordosis. The strongest predictor for lumbar lordosis was LDD (p < 0.0001) which is itself genetically determined in part. For thoracic kyphosis, BMD was strongly associated and remained so (for lumbar BMD) with the inclusion of age, showing BMD to be an independent risk factor. This work highlights the genetic factors influencing normal spine curvature in women.
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The Lancet. Global health · Oct 2015
Mortality risks in children aged 5-14 years in low-income and middle-income countries: a systematic empirical analysis.
Health priorities since the UN Millennium Declaration have focused strongly on children younger than 5 years. The health of older children (age 5-9 years) and younger adolescents (age 10-14 years) has been neglected until recently, especially in low-income and middle-income countries, and mortality measures for these age groups have often been derived from overly flexible models. We report global and regional empirical mortality estimates for children aged 5-14 years in low-income and middle-income countries, and compare them with ones from existing models. ⋯ The Lancet Commission on Investing in Health and the Bill & Melinda Gates Foundation.
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To determine benefits and harms of arthroscopic knee surgery involving partial meniscectomy, debridement, or both for middle aged or older patients with knee pain and degenerative knee disease. ⋯ PROSPERO CRD42014009145.
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Suicide is one of the top 10 leading causes of mortality among middle-aged women. Most work in the field emphasizes the psychiatric, psychological, or biological determinants of suicide. ⋯ Women who were socially well integrated had a more than 3-fold lower risk for suicide over 18 years of follow-up.