Articles: traumatic-brain-injuries.
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Mayo Clinic proceedings · Oct 2013
High risk of gastrointestinal hemorrhage in patients with epilepsy: a nationwide cohort study.
To examine the association between epilepsy and gastrointestinal hemorrhage. ⋯ Epilepsy is an independent determinant for gastrointestinal hemorrhage in a chronological and severity-dependent pattern. We urge the development of an adequate surveillance policy and strategy for the early prevention of gastrointestinal hemorrhage in epileptic patients.
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Experimental neurology · Oct 2013
Modeling clinically relevant blast parameters based on scaling principles produces functional & histological deficits in rats.
Blast-induced traumatic brain injury represents a leading cause of injury in modern warfare with injury pathogenesis poorly understood. Preclinical models of blast injury remain poorly standardized across laboratories and the clinical relevance unclear based upon pulmonary injury scaling laws. Models capable of high peak overpressures and of short duration may better replicate clinical exposure when scaling principles are considered. ⋯ Furthermore, hematoxylin and eosin staining showed the presence of red blood cells within the parenchyma and red, swollen neurons following blast injury. Exposure to blast with 90.10 PSI peak reflected overpressure resulted in immediate mortality associated with extensive intracranial bleeding. This work demonstrates one of the first examples of blast-induced brain injury in the rodent when exposed to a blast wave scaled from human exposure based on scaling principles derived from pulmonary injury lethality curves.
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Ann Fr Anesth Reanim · Oct 2013
Case Reports[Use of ECMO (extracorporeal membrane oxygenation) in a traumatic brain injured patient with severe hypoxemia.]
Traumatic brain injuries are fairly sensitive to hypoxia. For patient with associated lung and brain traumas, different means used to improve oxygen blood level are poorly described. We report the use of ECMO in a refractory hypoxemia occurred to a multitrauma young patient with neurological lesions.
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Arch Phys Med Rehabil · Oct 2013
Randomized Controlled Trial Multicenter StudyMedical complications during inpatient rehabilitation among patients with traumatic disorders of consciousness.
To assess the incidence of medical complications in patients with recent traumatic disorders of consciousness (DOCs). ⋯ Patients with DOCs have a high rate of medical complications early after injury. Many of these complications require brain injury expertise for optimal management. Active medical management appears to contribute to the reduction in new complications. An optimal system of care for DOC patients must provide expert medical management in the early weeks after injury.
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Arch Phys Med Rehabil · Oct 2013
Multicenter StudyRationale and design of the prospective German registry of outcome in patients with severe disorders of consciousness after acute brain injury.
To describe the rationale and design of a new patient registry (Koma Outcome von Patienten der Frührehabilitation-Register [KOPF-R; Registry for Coma Outcome in Patients Undergoing Acute Rehabilitation]) that has the scope to examine determinants of long-term outcome and functioning of patients with severe disorders of consciousness (DOC). ⋯ The KOPF-R aspires to contribute prospective data on prognosis in severe DOC.