Articles: mass-screening.
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J. Natl. Cancer Inst. · Sep 2013
Multicenter StudyCost-effectiveness of screening women with familial risk for breast cancer with magnetic resonance imaging.
To reduce mortality, women with a family history of breast cancer are often screened with mammography before age 50 years. Additional magnetic resonance imaging (MRI) improves sensitivity and is cost-effective for BRCA1/2 mutation carriers. However, for women with a family history without a proven mutation, cost-effectiveness is unclear. ⋯ Screening with MRI may improve survival for women with familial risk for breast cancer but is expensive, especially in the youngest age categories.
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The lancet oncology · Jul 2013
Multicenter StudyAssessment of volumetric growth rates of small colorectal polyps with CT colonography: a longitudinal study of natural history.
The clinical relevance and in-vivo growth rates of small (6-9 mm) colorectal polyps are not well established. We aimed to assess the behaviour of such polyps with CT colonography assessments. ⋯ US National Institutes of Health, National Cancer Institute.
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Randomized Controlled Trial Multicenter Study Comparative Study
Impact of the European Randomized Study of Screening for Prostate Cancer (ERSPC) on prostate-specific antigen (PSA) testing by Dutch general practitioners.
To determine the impact of the European Randomized Study of Screening for Prostate Cancer (ERSPC) publication in 2009 on prostate-specific antigen (PSA) level testing by Dutch general practitioners (GPs) in men aged ≥40 years. ⋯ After the ERSPC publication primary PSA testing as well as follow-up testing decreased. Follow-up testing seemed not to be adequate after an abnormal PSA result. The reasons for this remain unclear.
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AJR Am J Roentgenol · Jul 2013
Multicenter StudyEffective dose assessment for participants in the National Lung Screening Trial undergoing posteroanterior chest radiographic examinations.
The National Lung Screening Trial (NLST) is a multicenter randomized controlled trial comparing low-dose helical CT with chest radiography in the screening of older current and former heavy smokers for early detection of lung cancer. Recruitment was launched in September 2002 and ended in April 2004, when 53,454 participants had been randomized at 33 screening sites. The objective of this study was to determine the effective radiation dose associated with individual chest radiographic screening examinations. ⋯ The effective dose for participant NLST chest radiographic examinations was determined and is of specific interest in relation to that associated with the previously published NLST low-dose CT examinations conducted during the trial.
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Randomized Controlled Trial Multicenter Study Comparative Study
Promoting colorectal cancer screening discussion: a randomized controlled trial.
Provider recommendation is a predictor of colorectal cancer (CRC) screening. ⋯ The computer-delivered tailored intervention was more effective than a nontailored brochure at stimulating patient-provider discussions about CRC screening. Those who received the computer-delivered intervention also were more likely to have a CRC screening test (fecal occult blood test or colonoscopy) ordered by their PCP.