Articles: child.
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J Am Acad Child Adolesc Psychiatry · Feb 1997
Randomized Controlled Trial Clinical TrialNonpharmacological response in hospitalized children with conduct disorder.
There is a paucity of research regarding the effects of hospitalization and/or the response to placebo in children with conduct disorder who are hospitalized for chronic and severe aggression. However, many children with this problem are hospitalized and immediately begin pharmacotherapy. In this report, the effects of hospitalization and placebo administration were examined. ⋯ This finding has important treatment and research implications. Medication to treat aggression should not be initiated immediately upon hospitalization because improvements associated with hospitalization may be attributed inaccurately to pharmacotherapy, resulting in unnecessarily medicating children. A placebo baseline period is essential to decrease the risk of a type II error in pharmacological research concerning aggression.
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Randomized Controlled Trial Comparative Study Clinical Trial
Randomised controlled trial of treatment of chronic suppurative otitis media in Kenyan schoolchildren.
The outcomes of treatment of chronic suppurative otitis media (CSOM) are disappointing and uncertain, especially in developing countries. Because CSOM is the commonest cause of hearing impairment in children in these countries, an effective method of management that can be implemented on a wide scale is needed. We report a randomised, controlled trial of treatment of CSOM among children in Kenya; unaffected schoolchildren were taught to administer the interventions. ⋯ Our finding that dry mopping plus topical and systemic antibiotics is superior to dry mopping alone contrasts with that of the only previous community-based trial in a developing country, though it accords with findings of most other trials in developed countries. The potential role of antibiotics needs further investigation. Further, similar trials are needed to identify the most cost-effective and appropriate treatment regimen for CSOM in children in developing countries.
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Randomized Controlled Trial Clinical Trial
The use of oral midazolam in accident and emergency to reduce anxiety in children.
The injured child can react to a visit to the Accident and Emergency (A & E) department in many ways. The strange noise, people, environment or their frightened parents may be overwhelming for the child. The screaming, uncooperative child can be as hard to manage as the silent unpredictable child, and there are also the smiling, laughing 'you can do anything to me within reason' children. ⋯ The pharmacology of midazolam will be briefly looked at, within this article further detail is not necessary. The main discussion will be the introduction and the current use of oral midazolam in A & E at Leeds General Infirmary (LGI, UK). Some concerns and worries will be considered.
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The Journal of pediatrics · Jan 1996
Randomized Controlled Trial Comparative Study Clinical TrialA double-blind clinical trial comparing World Health Organization oral rehydration solution with a reduced osmolarity solution containing equal amounts of sodium and glucose.
To compare the safety and efficacy of an oral rehydration solution (ORS) containing 75 mmol/L of sodium and glucose each with the standard World Health Organization (WHO) ORS among Egyptian children with acute diarrhea. ⋯ The reduced osmolarity ORS has beneficial effects on the clinical course of acute diarrhea in children by reducing stool output, and the proportion of children with vomiting during the rehydration phase, and by reducing the need for supplemental intravenous therapy. These results provide support for the use of a reduced osmolarity ORS in children with acute noncholera diarrhea.
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Randomized Controlled Trial Clinical Trial
Zinc supplementation in young children with acute diarrhea in India.
In developing countries the duration and severity of diarrheal illnesses are greatest among infants and young children with malnutrition and impaired immune status, both factors that may be associated with zinc deficiency. In children with severe zinc deficiency, diarrhea is common and responds quickly to zinc supplementation. ⋯ For infants and young children with acute diarrhea, zinc supplementation results in clinically important reductions in the duration and severity of diarrhea.