Articles: postoperative-pain.
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Randomized Controlled Trial Comparative Study Clinical Trial
Comparative analgesic efficacy and tolerability of ketorolac tromethamine and glafenine in patients with post-operative pain.
In a randomized, single-dose, double-blind, parallel comparative trial of analgesic efficacy, 96 adult patients received either 10 mg ketorolac tromethamine or 400 mg glafenine orally the morning after surgery if they requested pain relief medication. Each patient provided a baseline pain assessment and then received the assigned medication. Patients assessed pain intensity and pain relief and reported any adverse events in interviews held 30 minutes after drug administration and then hourly for 6 hours. ⋯ The differences in overall response were statistically significant (p = 0.017). Fourteen (30%) patients who received ketorolac tromethamine and 17 (35%) who received glafenine reported adverse experiences that began or seemed to worsen after administration of the study drugs. The most prominent were drowsiness and sleeping, both of which are common in post-surgical patients.
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Scand J Thorac Cardiovasc Surg · Jan 1988
Randomized Controlled Trial Comparative Study Clinical TrialReduction of post-thoracotomy pain by cryotherapy of intercostal nerves.
In a prospective study, 144 patients undergoing thoracotomy were randomized to two groups: In 71 cases cryoanalgesia was applied intraoperatively to the intercostal nerves above and below the incision to relieve postoperative pain, and 73 (control group) received bupivacaine-adrenaline intercostal blockade at the end of the operation. The amount of administered narcotic and mild analgesics, the visual analogue pain scores, the need for further intercostal blockade and the number of postoperative bronchoscopies to clear retained secretion were significantly less in the cryoanalgesia group than in the controls. There were no late nerve complications after cryoanalgesia, which is recommended for routine use in thoracotomy.
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Randomized Controlled Trial Clinical Trial
Transcutaneous electrical nerve stimulation for pain relief following inguinal hernia repair: a controlled trial.
The efficacy of transcutaneous electrical nerve stimulation (TENS) in relieving postoperative pain has been assessed by means of a prospective randomized controlled trial in 62 male patients undergoing unilateral inguinal herniorrhaphy. Thirty-four patients received TENS and 28 patients received sham TENS for 48 h after the operation. ⋯ We were unable to detect any significant differences in these variables when the two groups were compared. These results do not support the use of TENS.
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Patient-controlled analgesia (PCA) has been studied extensively for the treatment of postoperative pain using narcotic analgesics. Butorphanol, a nonnarcotic injectable analgesic, has not previously been investigated using this drug delivery mechanism. ⋯ Most patients (84%) were able to obtain excellent postoperative pain relief. The role of butorphanol in the management of postoperative pain should be expanded to include patient-controlled drug delivery.