Articles: general-anesthesia.
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A review of the literature and of our recent data (obtained by computer-based analysis of multiple inert gas elimination) re-emphasizes the significant gas exchange disturbances found to occur during general anesthesia which develop for probably several reasons. In this report we suggest firstly that the reduction in functional residual capacity (FRC) may well be an effect of anesthesia just as is abnormal gas exchange. In other words, the reduction in FRC is not per se the cause of gas exchange disturbances, but rather occurs alongside them. ⋯ Such factors include altered hypoxic vasoconstriction, a change in airway secretions and clearance of those secretions, changes in bronchomotor tone, changes in surfactant activity, and alveolar volume loss due to rapid uptake of soluble anesthetic gases like nitrous oxide. To qualitatively and quantitatively distinguish amongst these various potential factors will require experimental protocols and techniques of a highly controlled and accurate nature. That in 1983 we still do not understand the basic mechanisms behind abnormal gas exchange during anesthesia attests to the difficulty of mounting such an experiment.
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Ann Fr Anesth Reanim · Jan 1984
[Anesthesia and intensive care in cardiac surgery. Activity at the French centers in 1982].
A national survey was carried out to inquire about the practice of anaesthesia and surgical intensive care in cardiac surgery in French hospitals. In 1982, 15,797 surgical procedures with cardiopulmonary bypass were collected; 1,360 and 555 were performed in children and infants respectively. Coronary surgery accounted for 46% of the total. ⋯ With the exception of arterial blood pressure monitoring, there was no consensus on the method or the extent of monitoring of patients undergoing cardiac surgery. A Swan-Ganz catheter was only used in 18% of cases. Neuroleptanalgesia was the anaesthetic technique most often used.
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Scand. J. Gastroenterol. Suppl. · Jan 1984
Effect of pentobarbital anesthesia and bile acids on cysteamine-induced duodenal and gastric ulcers in rats.
Cysteamine given three times within 8 h produced severe duodenal and gastric ulcers in female SIV rats. A pentobarbital anesthesia during the first 10 h prevented gastric ulcer formation without affecting duodenal ulcer. ⋯ Treatment with somatostatin significantly reduced the intensity of duodenal ulcer. The inhibition of cysteamine-induced gastric ulcer formation by pentobarbital does not seem to be due to a possible inhibition of duodenogastric reflux but more likely to an inhibition of central nervous stress reactions by anesthesia.