Articles: general-anesthesia.
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Anasthesiol Intensivmed Notfallmed Schmerzther · Feb 1995
Review[Inhalation anesthesia and intravenous anesthesia from the medical and economic viewpoint].
The unique pharmacokinetic properties of propofol gave rise to a widespread use of the technique of total intravenous anaesthesia. These properties of propofol are reviewed and compared to those of barbiturates and benzodiazepines. ⋯ The choice of an anaesthetic technique must not only be made with regard to medical implications; economical aspects have also to be taken into account without challenge to the quality of care. A consequent use of low-flow techniques and a market oriented purchase of drugs and disposables may allow cost savings in anesthesia.
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Complications related to wrong or improper perioperative positioning are preventable events. Nevertheless patients may suffer from these complications much more than from the original pathology. In a short review a focus is set on the prone and supine position. Finally remarks for prevention are added.
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The cellular and synaptic mechanisms that underpin the state of general anaesthesia are discussed. Anaesthetics act principally on synaptic processes and this provides a satisfactory basis for understanding their effects on neural networks. ⋯ Effects on action potential firing patterns also play a role in anaesthetic modulation of neuronal signalling. Many of these complex data can be explained in terms of altered ion channel function.