Articles: intensive-care-units.
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Randomized Controlled Trial Clinical Trial
Combined hemodilution and hypotension monitored with jugular bulb oxygen saturation, EEG, and ECG decreases transfusion volume and length of ICU stay for major orthopedic surgery.
To assess the efficacy and safety of hemodilution combined with induced hypotension during surgery. ⋯ Hemodilution combined with induced hypotension was safe and may reduce the need for transfusion and ICU admission.
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Randomized Controlled Trial Clinical Trial
Association of mortality with age of blood transfused in septic ICU patients.
To determine, retrospectively, the age of packed red blood cell (PRBC) units transfused to patients admitted to the ICU with the diagnosis of severe sepsis and to correlate this variable with outcome. ⋯ This is the first study to report a correlation of mortality with the age of PRBC transfused. The cause of this association is unclear. If this association is confirmed by a prospective randomised trial it would have major implications for the use of PRBC in severe sepsis.
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The Journal of pediatrics · Oct 1997
Randomized Controlled Trial Comparative Study Clinical TrialThe Pediatric Risk of Mortality III--Acute Physiology Score (PRISM III-APS): a method of assessing physiologic instability for pediatric intensive care unit patients.
To develop a physiology-based measure of physiologic instability for use in pediatric patients that has an expanded scale compared with the Pediatric Risk of Mortality (PRISM) III score. ⋯ The PRISM III-APS score is an expanded measure of physiologic instability that has been validated against mortality. Compared with PRISM III, PRISM III-APS should be more sensitive to small changes in physiologic status.
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Randomized Controlled Trial Clinical Trial
Effects of intrathecal opioid on extubation time, analgesia, and intensive care unit stay following coronary artery bypass grafting.
To determine if intrathecal opioid decreases time to extubation after coronary artery bypass surgery without compromising postoperative analgesia. ⋯ Intrathecal opioid can facilitate early extubation and discharge from the ICU without compromising analgesia or increasing myocardial ischemia.
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Critical care medicine · Apr 1997
Randomized Controlled Trial Clinical TrialA randomized, controlled trial of protocol-directed versus physician-directed weaning from mechanical ventilation.
To compare a practice of protocol-directed weaning from mechanical ventilation implemented by nurses and respiratory therapists with traditional physician-directed weaning. ⋯ Protocol-guided weaning of mechanical ventilation, as performed by nurses and respiratory therapists, is safe and led to extubation more rapidly than physician-directed weaning.