Articles: coronavirus.
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Many human viral diseases are a consequence of a zoonotic event. Some of the diseases caused by these zoonotic events have affected millions of people around the world, some of which have resulted in high rates of morbidity/mortality in humans. Changes in the viral proteins that function as ligands of the host receptor may promote the spillover between species. ⋯ The observed changes have significant effect on SARS-CoV-2 spike/ACE2 interaction and produce a reduction in the binding energy, compared to the one of the Bat-CoV to this receptor. The data presented in this study suggest a higher affinity of the SARS-Cov-2 spike protein to the human ACE2 receptor, compared to the one of Bat-CoV spike and ACE2. This could be the cause of the rapid viral spread of SARS-CoV-2 in humans.
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Health Promot Perspect · Jan 2020
Nigeria media framing of coronavirus pandemic and audience response.
Background: Part of the role of the media is to report any issue affecting the society to the masses. Coronavirus has become an issue of transnational concern. The importance of the media in the coverage of coronavirus disease 2019 (COVID-19) in Nigeria and its implications among Nigerian populace cannot be overestimated. ⋯ Finding further suggests that the framing pattern adopted by the newspapers helped Nigerians to take precautionary measures. Conclusion: Continuous reportage of COVID-19 has proved effective in creating awareness about safety and preventive measures thereby helping to 'flatten the curve' and contain the spread of the virus. However, the newspapers should avoid creating fear/panic in reporting the pandemic.
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To contain the coronavirus pandemic (COVID-19), a strict nationwide lockdown has been enforced and the health systems have been reorganized to deal with this entity. During this period, changes in the care of non-infectious diseases have been observed. Our aim was to describe the impact of the COVID-19 pandemic in the care of non-communicable diseases. ⋯ A meaningful decrease was found in coronary angioplasties (59%) and total percutaneous interventions (65%), and also a decrease in general surgeries (73%), and cardiac surgeries (58%). Although social distancing measures are a key public health strategy to flatten the infection curve, the observed decrease in medical visits and interventions may impact negatively on cardiovascular, cerebrovascular and cancer related morbidity and mortality. A collective effort is required to avoid the unintended consequences and collateral damage of the COVID-19 pandemic.