Articles: sepsis.
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Critical care medicine · Feb 2025
Association of Omega-3 Status With Long-Term Risk of Hospitalization for Sepsis.
Sepsis is a life-threatening condition characterized by a dysregulated host response to infection. Despite decades of clinical trials, there are no specific treatments; care of the nearly 50 million annual cases worldwide is limited to antimicrobials and supportive measures. A primary prevention strategy may therefore be of value. We hypothesized that higher premorbid omega-3 fatty acid levels would be associated with a reduced incidence of sepsis. ⋯ In this population-based cohort study, baseline eO3I was inversely associated with subsequent sepsis incidence. Given that omega-3 levels can be increased with dietary supplementation, primary prevention should be explored to mitigate the burden of sepsis.
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Journal of critical care · Feb 2025
Meta AnalysisHospital readmission after surviving sepsis: A systematic review of readmission reasons and meta-analysis of readmission rates.
To review the evidence regarding hospital readmission diagnoses and analyse related readmission rates following a sepsis admission. ⋯ Infection and sepsis are frequent readmission diagnoses for sepsis survivors, with one in 21 adult survivors readmitted for sepsis at 30-days. PROSPERO registration: CRD42023455851.