Articles: sepsis.
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Severe septicemia is commonly a catabolic disease process with increased energy demands and enhanced protein degradation. Septic ICU-patients are on the one hand dependent on a sufficient substrate application; on the other hand, however, the organism's tolerance against exogenous substrate application is very often diminished in these patients because of varying organ insufficiencies. Because septicemia is not a uniform type of illness with predictable organ dysfunctions, it is not possible to give recommendations for a specific nutritional diet in septic patients. Nutritional management must be adapted individually according to the type and the degree of organ dysfunctions associated with septicemia.
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Critical care clinics · Jul 1989
ReviewMultiple systems organ failure (MSOF): lessons learned from the adult respiratory distress syndrome (ARDS).
The relationship between ARDS and MSOF is explored. Models include that ARDS represents only one organ failing in MSOF, or that MSOF is a complication of ARDS owing to the development of infection and sepsis syndrome in these patients. Data are reviewed suggesting an important role of infection and sepsis syndrome in both models.
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Fulminant sepsis following splenectomy remains a major problem. Even with the administration of pneumococcal vaccine and prophylactic antibiotics fatalities still occur. A better understanding of the complex immunological function of the spleen, its preservation as much as possible during surgery, potent vaccine and perhaps more effective antibiotics will, hopefully, help reduce mortality in some of these cases in future.