Articles: covid-19.
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JMIR Bioinform Biotech · Jan 2020
Structural Basis for Designing Multiepitope Vaccines Against COVID-19 Infection: In Silico Vaccine Design and Validation.
The novel coronavirus disease (COVID-19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to the ongoing 2019-2020 pandemic. SARS-CoV-2 is a positive-sense single-stranded RNA coronavirus. Effective countermeasures against SARS-CoV-2 infection require the design and development of specific and effective vaccine candidates. ⋯ The present study is highly significant in terms of the molecular design of prospective CTL and HTL vaccines against SARS-CoV-2 infection with potential to elicit cellular and humoral immune responses. The epitopes of the designed MEVs are predicted to cover the large human population worldwide (96.10%). Hence, both designed MEVs could be tried in vivo as potential vaccine candidates against SARS-CoV-2.
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Arch Acad Emerg Med · Jan 2020
Daily Situation Report on Coronavirus disease (COVID-19) in Iran; March 25, 2020.
After detection of the first confirmed cases of COVID-19 in Iran, the National Committee on COVID-19 Epidemiology in Ministry of Health and Medical Education was established. This Committee is official source of gathering, analyzing, and reporting the COVID-19 data in Iran. The data of all sources in the country including, medical care monitoring center (MCMC), Hospitals' Information Systems (HIS), Laboratory portal, the data of the center for communicable disease control (MOH), as well as the data from community health centers are integrated and used in this regards. This factsheet contain daily situation report on coronavirus disease (covid-19) in Iran; March 25, 2020.
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Frontiers in psychology · Jan 2020
A Longitudinal Cohort Study Investigating Inadequate Preparation and Death and Dying in Nursing Students: Implications for the Aftermath of the COVID-19 Pandemic.
To investigate how changes in the levels of preparedness and experiences of death and dying influence nursing students' mental health. ⋯ The results of this study suggest that it is not the increase in death and dying per se that causes mental health difficulties, but that it is instead the experience of high levels of death and dying in combination with inadequate preparation. The data are considered within the context of the COVID-19 pandemic, with both inadequate preparation and the scale of death and dying being two significant stressors during the emergency period.