Articles: function.
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Barriers to recruiting and retaining acutely ill older adults in clinical research include complexity of illness, fatigue, and early discharge. ⋯ Multiple barriers to the recruitment and retention of older adults hospitalized for acute heart failure were identified. Strategies are needed to augment recruitment and retention efforts, including expanding the number of data collection sites and allocating sufficient support resources.
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Journal of critical care · Aug 2016
EditorialNeuroscience and awareness in the dying human brain: Implications for organ donation practices.
Consciousness has 2 components: wakefulness (arousal) and awareness (perception of the self and the external environment). Functional neuroimaging has identified 2 distinctive functional networks that mediate external awareness of the surrounding environment and internal awareness of the self. Recent studies suggest that awareness is not always associated with wakefulness. ⋯ This aligns with the 5-minute no-touch time after the loss of arterial pulse, the current circulatory standard of death determination in non-heart-beating organ donation. We argue that the capacity for awareness may not be irreversibly lost after a relatively brief period of cessation of systemic circulation, and outline empirical data in support of the claim that awareness without wakefulness may be present. Obviously, if correct, this will have practical and ethical implications on organ donation practices.