Articles: sars-cov-2.
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Singapore medical journal · Jun 2023
Meta AnalysisExtrapulmonary manifestations and complications of severe acute respiratory syndrome coronavirus-2 infection: a systematic review.
We aimed to describe the extrapulmonary manifestations of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection, including their frequency, onset with respect to respiratory symptoms, pathogenesis and association with disease severity. ⋯ Although the systemic manifestations of SARS-CoV-2 infection are variegated, they are deeply interwoven by shared mechanisms. Two phases of extrapulmonary disease were identified: (a) an early phase with possible gastrointestinal, ocular and cutaneous involvement; and (b) a late phase characterised by multiorgan dysfunction and clinical deterioration. A clear, multidisciplinary consensus to define and approach thromboinflammation and cytokine release syndrome in SARS-CoV-2 is needed.
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Revista clínica española · Jun 2023
Case Reports[SARS-CoV-2 antibodies after booster vaccination. Identification of subgroups with poor response].
To determine which patients within the high-risk group are most likely to have insufficient post-vaccination immunity. ⋯ Patients treated with antiCD20 drugs, hematologic patients and transplanted patients (mainly lung and kidney) have a higher risk of not achieving post-vaccination immunity. It is essential to identify them in order to individualize and optimize their management.