Articles: sars-cov-2.
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A total of 262 COVID-19-confirmed patients and 157 healthy controls were included in the study. ⋯ The mean vitamin D level in the COVID-19 group (12.8±8.9 ng/mL) was significantly lower than the control group (15.2±12.1 ng/mL) (p=0.015). The rate of those with vitamin D levels below 10 ng/mL in the COVID- 19 group (49.6%) was significantly higher than the control group (39.5%) (p=0.044). In the logistic regression analysis, it was found that those with a vitamin D level below 10 ng/mL had a 1.508-fold increased risk of COVID-19 compared to those who had 10 ng/mL and above (Odds ratio: 1.01-2.252). According to the risk analysis, those who have vitamin D levels below 20 ng/mL are 1,224 times higher than those who have 20 ng/mL and above; those under 30 ng/mL were found to have an increased risk of 2.01 times compared to those of 30 ng/mL and above. CONCLUSİONS: From the point of view of the literature data, we think that the findings we obtained may support researches that vitamin D level is significantly associated with both COVID-19 and other infections and many serious autoimmune and malignant diseases. As a result, rehabilitation programs on vitamin D deficiency should be organized and the society should be raised. KEY WORDS: Covid-19, Vitamin D25 (Oh) D.
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Frontiers in psychology · Jan 2020
COVID-19: Presumed Infection Routes and Psychological Impact on Staff in Administrative and Logistics Departments in a Designated Hospital in Wuhan, China.
Objective: Our aim was to explore the presumed infection routes and psychological impact of COVID-19 on staff in administrative and logistics departments (ALDs). Methods: We gathered data from all 18 staff members with COVID-19 in ALDs in Zhongnan Hospital of Wuhan University, China. The baseline, job before diagnosis, presumed infection environment, use of protective equipment, and psychological status before and after diagnosis were collected and analyzed. ⋯ There was no significant difference in psychological impact among the three groups, but uninfected staff members were fully aware of the seriousness of the epidemic. Conclusions: Effective protective measures should be taken for staff members in ALDs. Psychological interventions are very important to help infected staff members in ALDs cope with psychological distress.
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This study is to investigate the risk prediction of severe or critical events of COVID-19 in older adults in China and provide the evidence to support the management of older adults with COVID-19. ⋯ D-dimer and CD4 cells either by themselves or in combination have demonstrated predictive value in risk stratification as well as established the prognosis of severe or critical illness in older adults with COVID-19.
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A false-negative case of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is defined as a person with suspected infection and an initial negative result by reverse transcription-polymerase chain reaction (RT-PCR) test, with a positive result on a subsequent test. False-negative cases have important implications for isolation and risk of transmission of infected people and for the management of coronavirus disease 2019 (COVID-19). We aimed to review and critically appraise evidence about the rate of RT-PCR false-negatives at initial testing for COVID-19. ⋯ Protocol available on the OSF website: https://tinyurl.com/vvbgqya.
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Coronavirus disease 2019 (COVID 19) is an emerging infectious disease caused by a novel coronavirus SARS-CoV2 that was first identified in Wuhan, China 2019 and that led to a worldwide pandemia. In addition to typical respiratory signs (dry cough, shortness of breathing), some patients may develop gastrointestinal and hepatological complications including diarrhea or acute hepatitis, respectively. Due to the close contact to the patient's secretion, the gastroenterologists are at increased risk of getting the infection. ⋯ Endoscopy personnel should reduce exposure hazards by keeping a distance from the patient and using gloves, face masks, face shields and gowns. Taking into the consideration the fact that the virus proliferates in the gastrointestinal (GI) tract, special attention should be given to handling with stool specimens. In patients obtaining FMT for recurrent C. difficile infection, recommended screening measures include donor's medical history and testing for SARS-CoV-2 presence in pharyngeal and stool specimens.