Articles: sars-cov-2.
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Cochrane Db Syst Rev · Nov 2020
Review Meta AnalysisRoutine laboratory testing to determine if a patient has COVID-19.
Specific diagnostic tests to detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and resulting COVID-19 disease are not always available and take time to obtain results. Routine laboratory markers such as white blood cell count, measures of anticoagulation, C-reactive protein (CRP) and procalcitonin, are used to assess the clinical status of a patient. These laboratory tests may be useful for the triage of people with potential COVID-19 to prioritize them for different levels of treatment, especially in situations where time and resources are limited. ⋯ Although these tests give an indication about the general health status of patients and some tests may be specific indicators for inflammatory processes, none of the tests we investigated are useful for accurately ruling in or ruling out COVID-19 on their own. Studies were done in specific hospitalized populations, and future studies should consider non-hospital settings to evaluate how these tests would perform in people with milder symptoms.
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Review Meta Analysis
Chloroquine and Hydroxychloroquine for the Treatment of COVID-19: a Systematic Review and Meta-analysis.
There is no effective therapy for COVID-19. Hydroxychloroquine (HCQ) and chloroquine (CQ) have been used for its treatment but their safety and efficacy remain uncertain. ⋯ The available evidence suggests that CQ or HCQ does not improve clinical outcomes in COVID-19. Well-designed randomized trials are required for assessing the efficacy and safety of HCQ and CQ for COVID-19.
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Environmental pollution · Nov 2020
Meta AnalysisThe effect of latitude and PM2.5 on spreading of SARS-CoV-2 in tropical and temperate zone countries.
The present work describes spreading of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) at the tropical and temperate zones which are explained based on insolation energy, Particulate Matter (PM2.5), latitude, temperature, humidity, Population Density (PD), Human Development Index (HDI) and Global Health Security Index (GHSI) parameters. In order to analyze the spreading of SARS-CoV-2 by statistical data based on the confirmed positive cases which are collected between December 31, 2019 to April 25, 2020. The present analysis reveals that the outbreak of SARS-CoV-2 in the major countries lie on the Equator is 78,509 cases, the countries lie on the Tropic of Cancer is 62,930 cases (excluding China) and the countries lie on the Tropic of Capricorn is 22,842 cases. ⋯ In temperate zone countries, the concentration of PM2.5 at below 20 μg/m3 has higher spreading rate of SARS-CoV-2 cases. The effect of insolation energy and PM2.5, it is confirmed that the spreading of SARS-CoV-2 is explained by dumb-bell model and solid/liquid interface formation mechanism. The present meta-analysis also focuses on the impact of GHSI, HDI, PD and PM2.5 on spreading of SARS-CoV-2 cases.