Articles: sars-cov-2.
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For initial cognitive diagnostics in the practice, various screening tools in the form of short paper-pencil-tests are available. Such initial screenings take between 5 and 15 minutes, but do not replace detailed neuropsychological diagnostics. Of the screening-tools reviewed, DemTect is suitable for suspected early onset dementia, while MMSE and MoCA cover other cognitive domains in greater detail. ⋯ A more comprehensive diagnosis of dementia is not possible with the screening tools reviewed. However, they can help to decide whether a detailed dementia analysis is necessary or whether one can wait with it. The screening methods reviewed are freely available on the internet.
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The SARS-CoV-2 omicron variant of concern was identified in South Africa in November, 2021, and was associated with an increase in COVID-19 cases. We aimed to assess the clinical severity of infections with the omicron variant using S gene target failure (SGTF) on the Thermo Fisher Scientific TaqPath COVID-19 PCR test as a proxy. ⋯ The South African Medical Research Council, the South African National Department of Health, US Centers for Disease Control and Prevention, the African Society of Laboratory Medicine, Africa Centers for Disease Control and Prevention, the Bill & Melinda Gates Foundation, the Wellcome Trust, and the Fleming Fund.
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Randomized Controlled Trial Multicenter Study
Efficacy of the adjuvanted subunit protein COVID-19 vaccine, SCB-2019: a phase 2 and 3 multicentre, double-blind, randomised, placebo-controlled trial.
A range of safe and effective vaccines against SARS CoV 2 are needed to address the COVID 19 pandemic. We aimed to assess the safety and efficacy of the COVID-19 vaccine SCB-2019. ⋯ Clover Biopharmaceuticals and the Coalition for Epidemic Preparedness Innovations.