Articles: prospective-studies.
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Am. J. Respir. Crit. Care Med. · Jun 2014
Multicenter Study Observational StudyRole of Sleep Apnea and CPAP therapy in the incidence of stroke or coronary heart disease in women.
It is unknown whether obstructive sleep apnea (OSA) may be a risk factor for incident cardiovascular events in women. ⋯ In women, untreated OSA is associated with increased incidence of serious cardiovascular outcomes, particularly incident stroke. Adequate CPAP treatment seems to reduce this risk.
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Critical care medicine · Jun 2014
Multicenter Study Observational StudyArterial Blood Gas Tensions After Resuscitation From Out-of-Hospital Cardiac Arrest: Associations With Long-Term Neurological Outcome.
In patients resuscitated after out-of-hospital cardiac arrest, mean 24 hour PaCO2 predicted good outcome, specifically time spent with PaCO2 > 45 mmHg. No similar associations could be found between mean 24 h PaO2 and outcome.
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Am. J. Respir. Crit. Care Med. · May 2014
Multicenter Study Comparative StudyPathway From Central Obesity to Childhood Asthma: Physical Fitness and Sedentary Time Are Leading Factors.
Available prospective studies of obesity and asthma have used only body mass index (BMI) as an indicator for adiposity; studies using detailed obesity measures are lacking, and the role of physical fitness level and sedentary time remains unexplored in the link between obesity and asthma. ⋯ Central obesity measures should be incorporated in childhood asthma risk predictions. Children are encouraged to increase their physical fitness levels and reduce their sedentary time to prevent central obesity-related asthma.
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Anesthesia and analgesia · May 2014
Randomized Controlled Trial Multicenter StudyA pilot study for a prospective, randomized, double-blind trial of the influence of anesthetic depth on long-term outcome.
Greater depth of anaesthesia may be associated with a higher incidence of wound infection, mortality and composite risk of complications.
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Multicenter Study
A Simple Clinical Decision Rule To Rule Out Appendicitis In Patients With Nondiagnostic Ultrasound Results.
The objective was to identify a set of clinical features that can rule out appendicitis in patients with suspected acute appendicitis and nondiagnostic ultrasound (US) results, allowing safe discharge and next-day reevaluation without initial computed tomography (CT) or magnetic resonance imaging (MRI). ⋯ This newly developed CDR significantly reduces the probability of appendicitis in a large subgroup of patients with negative or inconclusive US results. These patients can be safely discharged for outpatient reevaluation without further initial imaging if proper follow-up is available. This could assist in lowering the number of ED imaging investigations in patients with suspected appendicitis.