Articles: outcome.
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This retrospective review examined the influence of delay to recompression on mild/moderate neurological decompression sickness (DCS) in divers, as a pilot for an abandoned prospective study. ⋯ Neither more HBOT nor a worse outcome of DCS could be related to delay to treatment longer than 17 hours. The amount of oxygen that had to be administered in total during the whole HBOT course was lower in cases that responded better to the initial HBOT.
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The promising results of the Solitaire Flow Restoration (FR) With the Intention for Thrombectomy (SWIFT) trial recently led toFood and Drug Administration (FDA) approval of theSolitaire FR stent retriever device for recanalization of cerebral vessels in patients with acute ischemic stroke. ⋯ Our study shows that a variety of other endovascular approaches are used in conjunction with Solitaire FR in actual practice in the United States.Early postmarket results suggest that Solitaire FR is an effective tool for endovascular treatment of acute ischemic stroke.
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Psychological distress can trigger acute coronary syndromes and sudden cardiac death in vulnerable patients. The primary pathophysiological mechanism that plays a role in stress-induced cardiac events involves the autonomic nervous system, particularly disproportional sympathetic activation and parasympathetic withdrawal. This article describes the relation between psychological distress and autonomic nervous system function, with a focus on subsequent adverse cardiovascular outcomes. ⋯ Results of the systematic review indicate that the primary brain areas involved in the autonomic component of the brain-heart association are the insula, medial prefrontal cortex, and cerebellum (based on 121 participants across three studies that fitted the inclusion criteria). Other areas involved in stress-induced autonomic modulation are the (anterior) cingulate cortex, parietal cortex, somatomotor cortex/precentral gyrus, and temporal cortex. The interaction between central and autonomic nervous system responses may have implications for further investigations of the brain-heart associations and mechanisms by which acute and chronic psychological distress increase the risk of myocardial infarction, cardiac arrhythmias, and sudden cardiac death.
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Atrial fibrillation has evolved from being a novel unproven procedure to being an important treatment option for patients with symptomatic atrial fibrillation. Atrial fibrillation ablation is an appropriate treatment option for patients with symptomatic atrial fibrillation, particularly if they have failed one or more trials of antiarrhythmic drug therapy. While much has been learned about the optimal technique and outcomes for catheter ablation of paroxysmal atrial fibrillation; catheter ablation of atrial fibrillation in patients with long standing persistent atrial fibrillation remains in its infancy. ⋯ First, we will review the various ablation strategies, which have been employed and proposed for ablation of long standing persistent atrial fibrillation. Second, the methodology, results and outcomes of the major studies were reviewed in detail, which have reported outcomes of ablation in this patient population. And finally, some conclusions were drawn regarding where we stand and where the knowledge gaps remain as we seek to improve ablation outcomes in this population of AF patients.