Articles: colic.
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Randomized Controlled Trial Comparative Study
Intravenous morphine plus ketorolac is superior to either drug alone for treatment of acute renal colic.
To study the efficacy of intravenous ketorolac, morphine, and both drugs in combination in reducing pain in acute renal colic. ⋯ A combination of morphine and ketorolac offered pain relief superior to either drug alone and was associated with a decreased requirement for rescue analgesia.
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The Journal of urology · May 2006
Randomized Controlled TrialTranscutaneous electrical nerve stimulation: an effective treatment for pain caused by renal colic in emergency care.
Acute renal colic is one of the most anguishing forms of pain in humans. We hypothesized that TENS is an effective pain treatment in patients with acute renal colic. ⋯ This trial shows that local TENS is a rapid and effective treatment for renal colic pain. We found TENS to be a good nondrug therapy under the difficult circumstances of out of hospital rescue.
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The Journal of urology · Sep 2005
Randomized Controlled Trial Comparative Study Clinical TrialA double-blind, placebo controlled comparison of the morphine sparing effect of oral rofecoxib and diclofenac for acute renal colic.
We compared the morphine sparing effect of a single dose of 50 mg oral rofecoxib, 3, 8-hourly doses of 50 mg diclofenac and placebo for acute renal colic. ⋯ No clinically relevant morphine sparing effect was seen in patients with renal colic treated with 50 mg oral diclofenac every 8 hours or a single dose of 50 mg rofecoxib as a representative of the specific inhibitors of cyclooxygenase-2.
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ANZ journal of surgery · Jul 2004
Randomized Controlled Trial Comparative Study Clinical TrialComparison of the effect of diclofenac with hyoscine-N-butylbromide in the symptomatic treatment of acute biliary colic.
Although non-steroidal anti-inflammatory drugs (NSAID) and spasmolytics have been used to relieve biliary colic, the role of these drugs in the natural history of biliary colic has not been clarified. The objective of the present study is to compare the efficacy of intramuscular diclofenac with intramuscular hyoscine in the treatment of pain of acute biliary colic, and to study their role in the natural history of biliary colic and in the prevention of cholelithiasis-related complications. ⋯ In patients with biliary colic, diclofenac gives much faster and more effective pain relief in a significantly larger number of patients as compared with hyoscine. Most remarkably, diclofenac can prevent progression of biliary colic to acute cholecystitis in a significant number of patients.
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Clinical therapeutics · Jul 2004
Randomized Controlled Trial Clinical TrialComparison of cizolirtine citrate and metamizol sodium in the treatment of adult acute renal colic: a randomized, double-blind, clinical pilot study.
Renal colic causes excruciating pain that provides a good clinical model of acute pain for the development of new analgesics. ⋯ Although this limited pilot study did not include an internal measure of sensitivity, relevant pain reduction was shown in the population of patients with suspected renal colic undergoing treatment with cizolirtine, suggesting the presence of analgesic activity. However, the efficacy of cizolirtine was found to be similar to that of metamizol. Treatments were well tolerated.