Articles: pain-clinics.
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Randomized Controlled Trial
Ultralow Dose of Naloxone as an Adjuvant to Intrathecal Morphine Infusion Improves Perceived Quality of Sleep but Fails to alter Persistent Pain: A Randomized, Double-blind, Controlled Study.
This randomized, cross-over, double-blind, controlled study of continuous intrathecal morphine administration in patients with severe, long-term pain addresses whether the supplementation of low doses of naloxone in this setting is associated with beneficial clinical effects. ⋯ To conclude, the addition of an ultralow dose of intrathecal naloxone (40 ng/24 h) to intrathecal morphine infusion in patients with severe, persistent pain improved perceived quality of sleep. We were not able to show any statistically significant effects of naloxone on pain relief, level of activity, or quality of life.
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Chronic pain is very common worldwide and can lead to disability, depression and absence from work. Catastrophizing has been proven to affect individuals' belief systems and coping strategies, and it is an essential risk factor for chronic pain. The pain catastrophizing scale (PCS) has been developed for the assessment of catastrophizing. However, a Chinese version of this scale is not available, and physicians are therefore unable to determine which patients are prone to catastrophizing. Additionally, the risk factors for catastrophizing are unknown. ⋯ The PCS has been linguistically translated into simplified Chinese and culturally adapted for a Chinese population with remarkable clinical acceptance, good construct validity, and excellent internal consistency and test-retest reliability. Education, pain duration, marital status, gender, income, and use of pain medications are important factors affecting catastrophizing.
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The present study aimed to identify predicting factors affecting experimental pain stimuli reduction by using 'EyeToy', which is an Immersive Virtual Reality System (IVRS). ⋯ It can be concluded that VR can serve as an effective manipulation for pain reduction in individuals with efficient CPM and in women. These findings constitute a promising platform for future research and hold potential for the improvement and facilitation of clinical treatment.
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Multicenter Study Clinical Trial
Pain intensity and interference with functioning and well-being in subgroups of patients with chronic pain treated with once-daily hydrocodone tablets.
A previous 52-week trial of patients with chronic noncancer, non-neuropathic pain (CNNP) showed clinically meaningful improvement in pain intensity, pain interference, and physical health-related quality of life (HRQL) following daily treatment with an extended-release, once-daily hydrocodone (Hysingla(®) ER; HYD) bitartrate tablet. ⋯ Regardless of subgroup, patients with CNNP treated with HYD showed clinically meaningful improvements in pain intensity, pain interference, and physical HRQL, although not in mental HRQL or sleep quality. Improvements were generally larger for opioid-naïve patients and patients with severe baseline pain.
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Observational Study
Role of acute pain service in optimizing postoperative pain relief in a tertiary care teaching hospital.
To assess the frequency and types of adjustments that acute pain service makes to postoperative analgesic regimes to improve pain relief or treat side effects. ⋯ Acute Pain Service played an important role in improving the quality of postoperative pain relief and management of analgesia-related side effects. Regular feedback to the primary anaesthesiologist can lead to improved practices.