Articles: acetaminophen.
-
Paediatric anaesthesia · Jul 2010
Randomized Controlled TrialParental calculation of pediatric paracetamol dose: a randomized trial comparing the Parental Analgesia Slide with product information leaflets.
To compare the ability of parents to calculate and demonstrate the correct paracetamol (acetaminophen) dose, interval, and frequency for their child when using either product information leaflets or the Parental Analgesia Slide. ⋯ The Parental Analgesia Slide resulted in improved parental ability to calculate paracetamol dose, interval, and frequency while preserving their ability to demonstrate an accurate drug volume.
-
Korean J Anesthesiol · Jul 2010
Effect of pretreatment with acetaminophen on withdrawal movements associated with injection of rocuronium: a prospective, randomized, double-blind, placebo controlled study.
Withdrawal movement during rocuronium injection is a common, unresolved adverse effect. We aimed to investigate the effect of IV acetaminophen pretreatment on withdrawal movement during rocuronium injection. ⋯ Acetaminophen and lidocaine reduced the incidence of withdrawal movement after rocuronium injection compared with saline.
-
Randomized Controlled Trial Comparative Study
Comparison of efficacy and effectiveness between ULTRACET and tramadol/acetaminophen in acute postoperative pain after upper extremity surgery.
To compare the efficacy and effectiveness between ULTRACE, a new analgesic combination of tramadol/ acetaminophen, and tramadol/acetaminophen for acute postoperative pain after upper extremity surgery. ⋯ ULTRACET has more efficacy and fewer side effects when compared with tramadol and acetaminophen in acute postoperative pain surgery.
-
Eur Rev Med Pharmaco · Jul 2010
Comparative Study Controlled Clinical TrialAcetaminophen plus codeine compared to ketorolac in polytrauma patients.
The management of pain in polytrauma patients is mandatory. While non-steroidal anti-inflammatory drugs (NSAIDs) represent the most used drugs in polytrauma patients, their use may be associated with an increased risk of haemorrhage. Opioids may represent a valid alternative to NSAIDs either alone or in combination with acetaminophen. Whether their efficacy is comparable to that produced by NSAIDs in polytrauma patients has never been studied. ⋯ Acetaminophen plus codeine is effective in pain control in polytrauma patients at least in our series. It may represent a valid alternative to NSAIDs, especially in patients with a documented haemorrhage or with a high hemorrhagic risk.
-
Eur. J. Clin. Pharmacol. · Jul 2010
Clinical TrialParacetamol for intravenous use in medium--and intensive care patients: pharmacokinetics and tolerance.
We studied the pharmacokinetics of paracetamol and determine the incidence of hypotension after intravenous administration in medium- (MCU) and intensive care (ICU) patients. ⋯ Further research on differences in paracetamol pharmacokinetics between ICU and MCU patients is warranted, as these differences might result in differences in efficacy. Furthermore, administration of paracetamol i.v. as potential cause of hypotension in the critically ill patient must not be overlooked.