Articles: acetaminophen.
-
Acta Odontol. Scand. · Oct 1997
Clinical TrialPattern of self-administered paracetamol and codeine analgesic consumption after mandibular third-molar surgery.
Pattern of analgesic consumption after unilateral mandibular third-molar surgery was investigated in an open study in 201 patients. All patients were supplied with six analgesic tablets containing 500 mg paracetamol and 30 mg codeine. Instructions for use were given. ⋯ No difference in mean tablet consumption was found between compliant patients and those who delayed the intake of the first analgesic dose by more than 1 h. Predictor analysis showed the most powerful predictors to be preoperative depth of the third molar and moderate or heavy smoking. Thirteen per cent explanatory power of all predictors together was found.
-
J Marmara Univ Dent Fac · Sep 1997
Randomized Controlled Trial Comparative Study Clinical TrialClinical effects of diflunisal and paracetamol in impacted mandibular third molar surgery.
A double-blind, randomized, cross-over study to compare diflunisal and paracetamol for postoperative pain, swelling and trismus relief following impacted mandibular third molar surgery was designed. 25 patients received one of the drugs at one visit and the alternative at the other visit. First doses were given two hours preoperatively and continued twice daily for five days. ⋯ The degree of impaction, pain, swelling and mouth opening were assessed by standardized methods and possible adverse effects were also recorded separately. Statistical analysis was carried out by "Student's t test". (p < 0.01 statistically significant).
-
1. Paracetamol is increasingly involved in self-poisoning in the United Kingdom and remains a common cause of fatal poisoning. 2. To document the epidemiology and early management of paracetamol poisoning data were collected on consecutive patients with suspected paracetamol poisoning presenting to 6 hospitals in the North East of England over 12 weeks in 1994. 3. ⋯ One patient died, from arrhythmias caused by co-ingested dothiepin. 6. Paracetamol poisoning is common. Most cases do not have potentially toxic plasma paracetamol concentrations, but those who do often present late and antidotal treatment may be delayed inappropriately.