Articles: cations.
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An amendment to this paper has been published and can be accessed via the original article.
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The following article from Headache: The Journal of Head and Face Pain, "Prevalence and Burden of Headache Disorders: A Comparative Regional Study in China," by Ning Luo PhD, Yannan Fang PhD, Feng Tan MD, Qian Zhang MD, Daliang Zou MD, Xiutang Cao PhD, Xuehua Xu MD, Hua Bai MD, Jiangang Ou MD, Haike Wu MD, Zilong Chen MD, Yane Zhou MD, Saiying Wan MD, Yan Hong MD, Jingliang Wang MD, Minghui Ding MD, Aiwu Zhang PhD, Daoyuan Zhu MD, Jun Dun PhD, published online on November 10, 2010 (DOI: 10.1111/j.1526-4610.2010.01795.x) on Wiley Online Library (http://www.onlinelibrary.wiley.com), has been retracted per agreement between the authors, the journal's Editor-in-Chief, John F. Rothrock, and Wiley Periodicals, Inc. This retraction has been made due to the article having been erroneously submitted to the journal prematurely in non-final form and without all authors having agreed to publication.
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A growing need exists for reliable in-vivo measurement of neuroinflammation to better characterise the inflammatory processes underlying various diseases and to inform the development of novel therapeutics that target deleterious glial activity. PET is well suited to quantify neuroinflammation and has the potential to discriminate components of the neuroimmune response. However, there are several obstacles to the reliable quantification of neuroinflammation by PET imaging. ⋯ Tissue studies have also begun to clarify the meaning of changes in PET signal in some diseases. Furthermore, although PET imaging of neuroinflammation does not have an established clinical application, novel targets are under investigation and a small but growing number of studies have suggested that this imaging modality could have a role in drug development. Future studies are needed to further improve our knowledge of the cellular mechanisms that underlie changes in PET signal, how immune response contributes to neurological disease, and how it might be therapeutically modified.
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Multicenter Study
Monogenic variants in dystonia: an exome-wide sequencing study.
Dystonia is a clinically and genetically heterogeneous condition that occurs in isolation (isolated dystonia), in combination with other movement disorders (combined dystonia), or in the context of multisymptomatic phenotypes (isolated or combined dystonia with other neurological involvement). However, our understanding of its aetiology is still incomplete. We aimed to elucidate the monogenic causes for the major clinical categories of dystonia. ⋯ Else Kröner-Fresenius-Stiftung, Technische Universität München, Helmholtz Zentrum München, Medizinische Universität Innsbruck, Charles University in Prague, Czech Ministry of Education, the Slovak Grant and Development Agency, the Slovak Research and Grant Agency.