Articles: cations.
-
Degenerative cervical myelopathy (DCM) encompasses a spectrum of age-related conditions that result in progressive spinal cord injury through static and dynamic injury mechanisms. Through detailed review of MRIs from prospective AOSpine multicenter studies, the global prevalence of degenerative cervical pathologies of surgically treated DCM patients is reported. ⋯ DCM pathologies, including OPLL, are highly interrelated and rarely present in isolation. Females presented with milder evidence of DCM on MRI. There are also variances in the spectrum and prevalence of pathologies between geographical regions and these may be due to a multitude of causes.
-
It became increasingly necessary to rethink the value and clinical implication of traumatic brain injury (TBI) management guided by intracranial pressure (ICP) monitoring. ⋯ There were multiple differences between the ICP monitoring and no ICP monitoring groups regarding patient characteristics, injury severity, characteristics of CT scan, and hospital type. ICP monitoring in conjunction with ICP targeted therapies is significantly associated with lower mortality in some special TBI subgroups.
-
A porous bioresorbable polymer scaffold has previously been tested in preclinical animal models of spinal cord contusion injury to promote appositional healing, spare white matter, decrease posttraumatic cysts, and normalize intraparenchymal tissue pressure. This is the first report of its human implantation in a spinal cord injury patient during a pilot study testing the safety and feasibility of this technique (ClinicalTrials.gov Identifier: NCT02138110). ⋯ AIS, American Spinal Injury Association Impairment ScaleSCI, spinal cord injurytSCI, traumatic spinal cord injury.
-
Venous thromboembolism (VTE) is a common complication of traumatic brain injury (TBI) with an estimated incidence of 25% when chemoprophylaxis is delayed. The timing of initiating prophylaxis is controversial given the concern for hemorrhage expansion. The objective of this study was to determine the safety of initiating VTE chemoprophylaxis in patients with TBI within 24 hours of presentation. ⋯ Early (<24 hours) initiation of VTE chemoprophylaxis in patients with traumatic intracranial hemorrhage appears to be safe. Further prospective studies are needed to validate this finding.
-
Cerebrovascular surgery offers potentially lifesaving treatments for intracranial vascular pathology yet bears substantial risks in the form of perioperative complications and mortality. ⋯ AVM, arteriovenous malformationCI, confidence intervalNSQIP, National Surgical Quality Improvement ProjectOR, odds ratio.