Articles: critical-care.
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Randomized Controlled Trial Multicenter Study Clinical Trial
Pain and suffering in seriously ill hospitalized patients.
Previous studies had suggested a high prevalence of pain in hospitalized patients but had not specifically evaluated pain and other symptoms in seriously ill and older hospitalized patients. ⋯ Control of pain and other symptoms remains an important medical and ethical issue. Routine monitoring of pain and other symptoms should be linked to treatment strategies aimed at combinations of symptoms and tested to assuage concerns about side effects.
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Multicenter Study
[Outcome of patients with systemic rheumatic diseases admitted to intensive care units: a retrospective study of 39 cases].
Patients with systemic rheumatic diseases are rarely admitted in intensive care units and very few studies focusing on the prognosis of those patients have been published. ⋯ Even if severity scores of patients suffering from systemic diseases are higher at admission in intensive care units than those of other patients, there is no relevant reason to refuse critical care to these patients.
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Critical care medicine · Nov 1999
Randomized Controlled Trial Multicenter Study Comparative Study Clinical TrialThe effect of acidified enteral feeds on gastric colonization in critically ill patients: results of a multicenter randomized trial. Canadian Critical Care Trials Group.
To evaluate the effect of acidified enteral feeds on gastric colonization in critically ill patients compared with a standard feeding formula. ⋯ Acidified enteral feeds preserve gastric acidity and substantially reduce gastric colonization in critically ill patients. Larger studies are needed to examine its effect on ventilator-associated pneumonia and mortality.
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Multicenter Study Clinical Trial
[Molecular biology studies of a multicenter phase III study (SIC Study)].
Transcription factors adjust the up- and downregulation of inflammatory genes. Within the bounds of the SIC-study (Selenium in Intensive Care) the authors will investigate the role of transcription factors NF-kappa B and AP-1 in S. ⋯ S/septic patients. The goal of these investigations is the corroboration of therapy of septic patients with sodium selenite at the molecular biological level.
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To describe patients' and family members' perceptions of transfer from an intensive care unit (ICU). ⋯ Patients and family members perceived the transfer from the ICU as a significant and sometimes negative event.