Articles: pain.
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Comparative Study
A comparison of the McGill Pain Questionnaire in chronic and acute pain.
The McGill Pain Questionnaire (MPQ) is widely used in pain research and treatment. The internal structure of the questionnaire has been subjected to empirical investigation, with sensory and reactive factors documented. In the present study, questionnaire responses of 95 women experiencing acute (post episiotomy) pain are analyzed. ⋯ It is suggested that acute pain involves less differentiation of sensory, affective and evaluative language dimensions. Rating scales were also administered. Ratings of labor and episiotomy pain were uncorrelated indicating the importance of distinguishing between these in studying pain in the puerperium.
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Low back pain patients' responses to the McGill Pain Questionnaire (MPQ) were factor analyzed using the principal factor method and direct oblique rotation procedures. Four factors were extracted that accounted for 55% of the total variance. ⋯ The results provided positive evidence that the sensory pressure, evaluative, and affective-sensory factors that were previously identified are stable dimensions underlying the MPQ responses of low back pain patients. However, it is necessary to conduct further cross-validation studies using patients from a wide variety of treatment settings.
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Randomized Controlled Trial Clinical Trial
Analgesic efficacy of an ibuprofen-codeine combination.
Subjects who had undergone dental impaction surgery and who had moderate to severe postoperative pain were given, under double-blind, randomized conditions, a single dose of either codeine 60 mg, aspirin 650 mg, ibuprofen 400 mg, aspirin 650 mg + codeine 60 mg, ibuprofen 400 mg + codeine 60 mg, or placebo. A total of 249 subjects were included in the statistical analysis. On a report form, subjects recorded pain intensity, pain relief, and side effects hourly for four hours. ⋯ There was no notable difference in the frequency or intensity of side effects among the treatment groups, and no subject had to withdraw due to an adverse effect. This study again confirms the superiority of ibuprofen to aspirin and suggests that ibuprofen is at least as effective as an aspirin-codeine combination. Codeine added a small amount of additional analgesia when used in combination with ibuprofen.
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The analgesic effect of i.v. lignocaine was evaluated in five patients with clinical neuralgic pain of varying aetiology. The response was compared with that on concurrently-induced ischaemic pain, initially of the same intensity. ⋯ The results suggest a divergence in the specificity of the analgesic action of lignocaine i.v. according to the nature of the pain-inducing process. Disorders manifesting as deafferentation or central neuralgias appear to be affected favourably by lignocaine i.v. whereas pain of peripheral origin is unaffected by lignocaine, except at blood concentrations which approach toxic values.