Articles: ninos.
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Randomized Controlled Trial Multicenter Study
In T1D, weekly efsitora was noninferior to daily degludec for reducing HbA1c but increased severe hypoglycemia at 26 wk.
Endocrinology: [Formula: see text].
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Randomized Controlled Trial
In HFpEF, semaglutide reduced a composite of worsening HF or CV death.
GIM/FP/GP: [Formula: see text] Cardiology: [Formula: see text].
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Randomized Controlled Trial
In long-term users of benzodiazepine receptor agonists, direct-to-patient interventions vs. usual care reduced use at 6 mo.
GIM/FP/GP: [Formula: see text] Geriatrics: [Formula: see text].
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Randomized Controlled Trial
The Heidelberg Decision Aid for Patients with Lung Cancer (HELP)—Findings of a Randomized, Controlled Trial.
Advanced lung cancer typifies the challenges of participatory decision-making in oncology. With a limited prognosis for survival, the increasingly numerous and complex treatment options must continually be weighed against issues of fragility, quality of life, and the end of life. ⋯ Even though the intervention was perceived as helpful preparation for decision-making, it did not bring about any improvement in the high level of decisional conflict. With the continual development of new treatments and the associated increase in prognostic uncertainty, there is an important role for individualized patient information and the training of physicians in how to deal with uncertainty.
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Comment Randomized Controlled Trial Multicenter Study Comparative Study
A Digital Health Behavior Intervention to Prevent Childhood Obesity: The Greenlight Plus Randomized Clinical Trial.
Infant growth predicts long-term obesity and cardiovascular disease. Previous interventions designed to prevent obesity in the first 2 years of life have been largely unsuccessful. Obesity prevalence is high among traditional racial and ethnic minority groups. ⋯ A health literacy-informed digital intervention improved child weight-for-length trajectory across the first 24 months of life and reduced childhood obesity at 24 months. The intervention was effective in a racially and ethnically diverse population that included groups at elevated risk for childhood obesity.