Articles: anticholesteremic-agents-therapeutic-use.
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Despite evidence of the efficacy of cholesterol lowering medication, it is known there is suboptimal patient adherence to this medication. The aim of this study is to investigate patient knowledge, attitudes and experiences of their cholesterol lowering medication, and explore patient views regarding programs to support self management. ⋯ This study provides preliminary evidence that patients on long term statin therapy may have gaps in their knowledge about their condition and treatment options and a desire to be better informed.
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Randomized Controlled Trial
Activating peripheral arterial disease patients to reduce cholesterol: a randomized trial.
Peripheral arterial disease patients are less likely than other high-risk patients to achieve ideal low-density lipoprotein (LDL) cholesterol levels. This randomized controlled trial assessed whether a telephone counseling intervention, designed to help peripheral arterial disease patients request more intensive cholesterol-lowering therapy from their physician, achieved lower LDL cholesterol levels than 2 control conditions. ⋯ Telephone counseling that helped peripheral arterial disease patients request more intensive cholesterol-lowering therapy from their physician achieved greater LDL cholesterol decreases than an attention control arm that provided health information alone.
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Eur J Cardiovasc Prev Rehabil · Apr 2011
Prevention of coronary heart disease in primary medical care in Poland: results from the LIPIDOGRAM study.
To determine: (1) achievement of cholesterol therapy goals in patients receiving lipid-lowering drugs in Polish primary care between the years 2004 and 2006; (2) the characteristics of patients that are associated with attainment of these goals. ⋯ There was a measurable improvement in the effectiveness of hypercholesterolaemia treatment between 2004 and 2006 but the majority of patients remain inadequately treated, with goals not being achieved. There is a need to raise the standard of lipid-lowering management in Poland.
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Clinical cardiology · Feb 2011
Randomized Controlled TrialThe effects of statin monotherapy and low-dose statin/ezetimibe on lipoprotein-associated phospholipase A₂.
Many of the pleiotropic effects of statins remain to be elucidated. ⋯ Atorvastatin monotherapy was stronger at reducing plasma Lp-PLA₂ than the low-dose atorvastatin/ezetimibe combination after equivalent LDL-C lowering. This result may provide evidence of potential statin effects beyond the lowering of LDL-C.