Articles: human-experimentation-history.
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Review Historical Article
Unraveling the Tuskegee Study of Untreated Syphilis.
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Int. J. Radiat. Oncol. Biol. Phys. · Mar 1999
Comment Letter Historical ArticleThe study of untreated syphilis in the negro male: regarding Brawley IJROBP 40:5-8; 1998.
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Historical Article
The continuing legacy of the Tuskegee Syphilis Study: considerations for clinical investigation.
The Tuskegee Study, an observational study of over 400 sharecroppers with untreated syphilis, was conducted by the U. S. ⋯ The study became the longest (1932-1972) nontherapeutic experiment on humans in the history of medicine, and has come to represent not only the exploitation of blacks in medical history, but the potential for exploitation of any population that may be vulnerable because of race, ethnicity, gender, disability, age or social class. It is important for physicians who will be caring for an increasingly diverse nation to understand the lasting implications of this study for their patients, but the effects of the Tuskegee Syphilis Study are demonstrated most strikingly by unsuccessful attempts at improving representation of minority patients in clinical trials.