Articles: brain.
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Randomized Controlled Trial Multicenter Study Comparative Study Clinical Trial
Prediction of recovery from post-traumatic vegetative state with cerebral magnetic-resonance imaging.
The early post-traumatic vegetative state (VS) is compatible with recovery. Various clinical and laboratory tests have failed to predict recovery so we assessed the value of cerebral magnetic-resonance imaging (MRI) in prediction of recovery. ⋯ Cerebral MRI findings in the subacute stage after head injury can predict the outcome of the post-traumatic VS. Corpus callosum and dorsolateral brainstem lesions are highly significant in predicting non-recovery.
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Multicenter Study
Radiological aspects of gamma knife radiosurgery for arteriovenous malformations and other non-tumoural disorders of the brain.
The aims of the thesis were to investigate stereotaxic procedures in radiosurgery for cerebral arteriovenous malformations (AVMs) and radiation effects of single session high-dose irradiation delivered by gamma knife on the human brain. Investigation of gamma knife radiosurgery in 1,464 patients constitutes the data base of this thesis. High quality stereotaxic angiography is the gold standard targeting imaging in radiosurgery for cerebral AVMs, particularly for small AVMs or residual AVMs after other treatments. ⋯ Volume effects and depreciation of the steep isodose gradient are hypothesised as the leading factors of the inconsistency. Based on the in vivo assessment of the radiation effects observed on the basically normal human brain it is concluded that irradiation volume is strongly related to the radiation effects and is one of the important considerations in decision making for radiosurgery. Volume of brain tissue exposed to irradiation could be minimised and precision of targeting could be maximised provided that a proper stereotaxic imaging is used.(ABSTRACT TRUNCATED AT 400 WORDS)