Articles: anesthesia.
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Anesteziol Reanimatol · Sep 2008
Multicenter Study Clinical Trial[Efficacy and safety of sevoflurane in various anesthesia modes (according to the results of a multicenter study)].
The paper presents the results of the limited multicenter sevoflurane study initiated by Abbott Lab, which was conducted in 2006. The study was undertaken to examine the efficacy and safety of sevoflurane in various anesthesia modes in patients (ASA I-III) with surgical diseases during surgical interventions into abdominal and thoracic organs and lower extremities. The study covered 96 patients. The analysis indicates that the use of sevoflurane for mask induction and anesthetic maintenance is possible and safe for patients with ASA I-III.
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Randomized Controlled Trial Multicenter Study Comparative Study
Reversal of soft-tissue local anesthesia with phentolamine mesylate in pediatric patients.
The authors evaluated the safety and efficacy of a formulation of phentolamine mesylate (PM) as a local anesthesia reversal agent for pediatric patients. ⋯ PM can help dental clinicians shorten the post-treatment duration of soft-tissue anesthesia and can reduce the number of posttreatment lip and tongue injuries in children.
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Randomized Controlled Trial Multicenter Study Comparative Study
Reversal of soft-tissue local anesthesia with phentolamine mesylate in adolescents and adults.
The authors conducted two multicenter, randomized, double-blinded, controlled Phase III clinical trials to study the efficacy and safety of phentolamine mesylate (PM) in shortening the duration and burden of soft-tissue anesthesia. The study involved 484 subjects who received one of four commercially available local anesthetic solutions containing vasoconstrictors for restorative or scaling procedures. ⋯ Clinicians can use PM to accelerate reversal of soft-tissue anesthesia and the associated functional deficits.
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Multicenter Study
Multicentered study of model of anesthesia related adverse events in Thailand by incident report (The Thai Anesthesia Incidents Monitoring Study): results.
The Thai Anesthesia Incidents Monitoring Study (Thai AIMS) was aimed to identify and analyze anesthesia incidents in order to find out the frequency distribution, clinical courses, management of incidents, and investigation of model appropriate for possible corrective strategies. ⋯ Common factors related to incidents were inexperience, lack of vigilance, inadequate preanesthetic evaluation, inappropriate decision, emergency condition, haste, inadequate supervision, and ineffective communication. Suggested corrective strategies were quality assurance activity, clinical practice guideline, improvement of supervision, additional training, improvement of communication, and an increase in personnel.
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Minerva anestesiologica · Jul 2008
Randomized Controlled Trial Multicenter Study Comparative StudyLevobupivacaine plus fentanyl versus racemic bupivacaine plus fentanyl in epidural anaesthesia for lower limb surgery.
To compare the anaesthetic epidural effects of levobupivacaine plus fentanyl versus bupivacaine plus fentanyl in patients undergoing lower limb surgery. ⋯ Although both interventions showed similar anaesthetic effects, a higher proportion of patients receiving levobupivacaine lacked MB.