Articles: anesthesia.
-
Randomized Controlled Trial Clinical Trial
[Effectiveness of infiltration anesthesia of postoperative abdominal wound using bupivacaine solution for alleviation of postoperative pain].
In a group of 40 patients after abdominal operations a high effectiveness was noted of infiltrations anaesthesia of the postoperative wound with 0.5% bupivacaine solution for alleviation of pain and reduction of requirements for narcotics in early postoperative period (randomized study).
-
Randomized Controlled Trial Comparative Study Clinical Trial
Comparison of 1.5% enflurane with 1.25% isoflurane in oxygen for caesarean section: avoidance of awareness without nitrous oxide.
We examined the feasibility of administering nearly 100% oxygen throughout the induction-delivery period of general anaesthesia for 113 Caesarean sections. Isoflurane 1.25% was compared with 1.5% enflurane for maintenance of anaesthesia. ⋯ The three main criteria for a satisfactory general anaesthetic technique for Caesarean section were fulfilled, namely no maternal awareness, no undue depression of the fetus and no adverse effect on uterine contractility. Isoflurane and enflurane appear to be suitable anaesthetic agents for facilitating hyperoxygenation during Caesarean section.
-
Randomized Controlled Trial Comparative Study Clinical Trial
Changes in oxygen saturation during inhalation induction of anaesthesia in children.
Changes in oxygen saturation (SaO2) were studied during induction of anaesthesia in 48 healthy children receiving halothane or isoflurane for outpatient dental extractions. Substantial reductions in SaO2 occurred in more than 50% of the children given isoflurane and were associated with the irritant effects of this agent on the airway. SaO2 was largely unaltered during the use of halothane. These findings indicate that the airway complications caused by isoflurane may be associated with decreases in SaO2.
-
Randomized Controlled Trial Clinical Trial
Effect of diluting propofol on the incidence of pain on injection and venous sequelae.
The effect of diluting propofol in 5% dextrose on the incidence of i.v. injection pain was studied in 100 adult patients. Severe injection pain occurred in 32% (16 patients) who received undiluted propofol, compared with 10% (five patients) who received dilute propofol. We concluded that the dilution of propofol significantly reduced the incidence of severe pain during injection without increasing postoperative venous sequelae.
-
Randomized Controlled Trial Clinical Trial
Partial attenuation of hemodynamic responses to rapid sequence induction and intubation with labetalol.
The effectiveness of labetalol (a combination nonselective beta and alpha-1-adrenergic receptor antagonist) in modifying hemodynamic responses associated with rapid sequence induction and tracheal intubation was evaluated. In a double-blind study, 24 ASA physical status I or II male patients scheduled for elective surgery were given either IV labetalol, 0.25 mg/kg (n = 8) or 0.75 mg/kg (n = 8), or a saline placebo (n = 8). Five minutes later, patients were given oxygen by mask and IV vecuronium, 0.01 mg/kg. ⋯ Within 30 seconds after intubation, patients in all three groups exhibited increases in heart rate, mean arterial pressure, total peripheral resistance, and rate pressure product and a decrease in stroke volume. However, patients in the 0.25 and 0.75 mg/kg labetalol groups, compared to those in the placebo group, had significantly lower increases in peak heart rate (33 +/- 2 and 27 +/- 3 vs. 44 +/- 7 beats/minute), peak mean arterial pressure (38 +/- 6 and 38 +/- 7 vs. 58 +/- 7 mmHg), and peak rate pressure product (7,726 +/- 260 and 7,215 +/- 300 vs. 14,023 +/- 250 units). The results show that these doses of labetalol significantly blunt, but do not completely block, autonomic responses to rapid sequence induction and intubation.