Articles: critical-illness.
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Intensive care medicine · Jan 1993
Randomized Controlled Trial Clinical TrialParenteral nutrition in the critically ill: use of a medium chain triglyceride emulsion.
The study investigated the use of an intravenous lipid emulsion containing medium chain triglycerides (MCTs) in critically ill patients, and compared the effects with those of a conventional long chain triglyceride (LCT) preparation. ⋯ MCTs are rapidly hydrolysed and oxidised to fatty acids and ketones which can be readily utilised. This study indicates that intravenous lipid emulsion containing MCT are safe in critically ill patients and may have advantages over LCT. The number and range of patients studied was, however, small and larger studies are needed.
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Critical care medicine · Oct 1992
Randomized Controlled Trial Comparative Study Clinical TrialEffect of acidified enteral feedings on gastric colonization in the critically ill patient.
To evaluate the effect of acidified enteral nutritional formulas (feedings) on gastric colonization and pH in critically ill patients. ⋯ Acidified enteral feedings are effective in eliminating and preventing gastric colonization in critically ill patients. Further investigation is needed to assess its effect on nosocomial infection rates.
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Critical care medicine · May 1992
Randomized Controlled Trial Clinical TrialGastric colonization and pneumonia in intubated critically ill patients receiving stress ulcer prophylaxis: a randomized, controlled trial.
To study the effects of pharmacologically increasing gastric pH on gastric colonization and the development of pneumonia in intubated critically ill patients. ⋯ Pharmacologically increasing gastric pH increases the risk for developing pneumonia in intubated critically ill patients. The pneumonia occurs earlier than in untreated control patients.
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Surg Gynecol Obstet · Mar 1992
Randomized Controlled Trial Clinical TrialTolerance to enteral tube feeding diets in hypoalbuminemic critically ill, geriatric patients.
Tolerance of elemental (for example, Peptamen [PEP]) or free amino acid (for example, Vivonex TEN [VIV]) tube feeding diets is controversial, especially in the critically ill patient who is hypoalbuminemic. A prospective, randomized trial was conducted to compare differences between feeding PEP (n = 8) or VIV (n = 8) in critically ill, elderly (average age of 66 years) patients. Diets were administered through nasogastric or postpyloric feeding tubes. ⋯ Serum albumin concentrations upon initiation of the diets were 2.3 grams per deciliter in both groups. We conclude that tolerance to the two diets were similar because it was possible to feed enterally either PEP or VIV in critically ill, hypoalbuminemic patients (serum albumin concentrations of less than 2.5 grams per deciliter) successfully, irrespective of diet. Although there were more stools in the VIV group, this did not reduce compliance with the goals.
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Intensive care medicine · Jan 1992
Randomized Controlled Trial Comparative Study Clinical TrialIsoflurane for prolonged sedation in the intensive care unit; efficacy and safety.
To compare isoflurane with midazolam for prolonged sedation in ventilated patients. ⋯ Isoflurane is a useful agent for prolonged sedation of ventilated patients and does not have any adverse effect on the cardiorespiratory system or on hepatic, renal or adrenal function.