Articles: critical-illness.
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Intensive care medicine · Jun 1998
Multicenter Study Clinical TrialThe Apache III prognostic system: customized mortality predictions for Spanish ICU patients.
To customize the Acute Physiology and Chronic Health Evaluation (APACHE) III mortality equation for Spanish admissions to the intensive care unit (ICU) and evaluate its discrimination and calibration. ⋯ We have customized the APACHE III mortality prediction system for the Spanish population. This adapted model has demonstrated the requisite validation, calibration, and discrimination for its use among Spanish critical care patients.
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Critical care medicine · Jan 1998
Multicenter StudyEvaluation of two outcome prediction models on an independent database.
To evaluate the performance of the New Simplified Acute Physiology Score (SAPS II) and the admission Mortality Probability Model (MPM0) in a large independent database, using formal statistical assessment. ⋯ The original SAPS II and MPM0 models did not accurately predict mortality on an independent large international multicenter ICU patient database. Results of studies utilizing general outcome prediction models without previous validation in the target population should be interpreted with prudence.
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Critical care medicine · Oct 1997
Multicenter Study Comparative StudyLimitation of therapeutic activity in elderly critically ill patients. Project for the Epidemiological Analysis of Critical Care Patients.
To establish whether the age of patients admitted into the intensive care unit (ICU) influences the amount of therapy received. ⋯ Patients > 75 yrs of age represent a large proportion of patients in Spanish ICUs. Although their mortality rate and severity scores were higher than those values in younger patients, patients > 75 yrs of age received less therapy.
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Critical care medicine · Sep 1997
Multicenter StudyOutcome of pediatric intensive care at six centers in Mexico and Ecuador.
To improve understanding of the causes of morbidity and mortality among critically ill children in the countries studied. ⋯ For six pediatric ICUs in Mexico and Ecuador, mortality was significantly higher than predicted among lower-risk patients. Tracheal intubation, central catheters, pneumonia, sepsis, and nonsurgical status were associated with poor outcome for low-risk groups. We speculate that reducing the use of invasive central catheters and endotracheal intubation for lower-risk patients, coupled with improved infection control, could lower mortality rates in the population studied.
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Intensive care medicine · May 1997
Randomized Controlled Trial Multicenter Study Clinical TrialSaccharomyces boulardii prevents diarrhea in critically ill tube-fed patients. A multicenter, randomized, double-blind placebo-controlled trial.
To assess the preventive effect of Saccharomyces boulardii on diarrhea in critically ill tube-fed patients and to evaluate risk factors for diarrhea. ⋯ S. boulardii prevents diarrhea in critically ill tube-fed patients, especially in patients with risk factors for diarrhea.