Articles: subarachnoid-hemorrhage.
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Acta neurochirurgica · Jan 1981
Determination of tranexamic acid (AMCA) and fibrin/fibrinogen degradation products in cerebrospinal fluid after aneurysmal subarachnoid haemorrhage.
Six patients with recently ruptured intracranial aneurysms were treated preoperatively with tranexamic acid (AMCA). Two patients received 6 g daily in i.v. infusion, two had 6 g daily by i.v. injection, and two patients were given AMCA 9 g daily by mouth during the first week after bleeding. Serial assays of AMCA and fibrin/fibrinogen degradation products (FDP) in cerebrospinal fluid (CSF) were performed during 6--13 days after the initial subarachnoid haemorrhage (SAH). Judged from the decline in CSF-FDP, an assumed therapeutic level of greater than or equal to 1 mg/l of AMCA in CSF was reached within 24--36 hours after the first dose when the drug was administered intravenously and within 48 hours when the drug was given orally.
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J Comput Assist Tomogr · Dec 1980
Comparative StudyCranial computed tomography in subarachnoid hemorrhage: relationship between blood detected by CT and lumbar puncture.
We compared the results of cranial computed tomography (CT) and lumbar puncture (LP) in patients who had subarachnoid hemorrhage due to proven ruptured intracranial aneurysm. We found no correlation between the number of red blood cells in the cerebrospinal fluid collected by LP and the amount and extent of blood detected by CT.
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The case of a patient who suffered a nontraumatic subarachnoid hemorrhage (SAH) associated with normal angiography is reported. Three weeks later he developed an embolic stroke secondary to a nonhemolytic Staphylococcus epidermidis endocarditis of the mitral valve; thus, the SAH was the initial manifestation of bacterial endocarditis. Bacterial endocarditis should be considered a possible cause of SAH, especially in the 7% of patients with angiographically negative SAH.